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primary differential with concurrent infection or neoplasia possible as well as conditions like a hamartoma. Treatment and Outcome A dorsal rhinotomy and frontal sinusotomy with turbinectomy and nasal cavity debridement using a standard technique

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in Journal of the American Veterinary Medical Association

right parasternal short-axis transthoracic echocardiographic image of a 6-year-old Siberian Husky-mix dog examined for episodes of collapse with a subsequent diagnosis of vascular hamartoma. A mass (white arrow) is evident in the lumen of the PA at the

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in Journal of the American Veterinary Medical Association

were mild with no mitotic figures observed ( Figure 4 ). An incompletely excised nasal adenomatoid hamartoma was diagnosed on the basis of cytokeratin stain uptake and lack of an endothelial component. The location and histologic features were

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in Journal of the American Veterinary Medical Association

right), with facial bone lysis Lymphoplasmacytic inflammation Right dorsal paramedian region over caudal maxillary bone Mild mixed-cell inflammation 5 18 × 23 × 36-mm soft tissue mass of the right caudal nasal cavity Vascular hamartoma

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in Journal of the American Veterinary Medical Association

). H&E stain; bar = 50 μm. Morphologic Diagnosis and Case Summary Morphologic diagnosis and case summary: vascular hamartoma in the brainstem of a cow. Comments Hamartomas are focal malformations that resemble neoplasms and are

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in Journal of the American Veterinary Medical Association

Summary

Twenty-seven horses (and 1 mule) with 32 histologically confirmed cutaneous tumors were studied to evaluate the effects of intratumoral injection of cisplatin initiated at the time of surgery. As a result of surgery, 9 of the wounds were closed primarily (5 sarcoids, 4 carcinomas) and 23 were left open to granulate (16 sarcoids, 6 carcinomas, 1 hamartoma). Chemotherapy consisted of 4 treatment sessions of intratumoral injection of cisplatin in purified sesame oil at 2-week intervals. The first treatment session was administered intraoperatively. A controlled-release formulation of cisplatin in sesame oil was used to limit drug egress from the injection site. Dosage was 1 mg of cisplatin/cm3 of tissue. The mean relapse-free interval was 41 ± 3.7 months. The estimates of overall relapse-free survival rates were 92 ± 5% at 1 year and 77 ± 11% at 4 years. Cisplatin-related local toxicosis was minimal and wound healing was not compromised. Intratumoral injection of cisplatin appears safe and effective when administered in the perioperative period for selected tumors in equidae.

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in Journal of the American Veterinary Medical Association

were refined to include anomalous disease (vertebral hamartoma), neoplasia (osteosarcoma or fibrosarcoma), historical unwitnessed trauma (callous formation), or an infectious disease process (osteomyelitis). Figure 1— Sagittal (A) and transverse

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in Journal of the American Veterinary Medical Association

remainder of the surgery was unremarkable, and the cat recovered from anesthesia uneventfully. There was no growth on direct plating media and broth culture after 72 hours. Histologic examination of sections of the mass revealed a vascular hamartoma

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in Journal of the American Veterinary Medical Association