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is diet, particularly with regards to fat. 1,4 Alterations in fatty acids are known to occur in cardiomyopathy and CHF. For example, the healthy adult heart uses long-chain fatty acids as its major energy source, but in CHF, the heart reverts to a

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in American Journal of Veterinary Research

NSAIDs and corticosteroid medication may accelerate cartilage degeneration. 6 Results of several studies 7–13 have suggested that omega-3 fatty acids have beneficial effects in the treatment of rheumatoid arthritis. Dietary supplementation with fish

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in Journal of the American Veterinary Medical Association

reference to its involvement in β-oxidation of the long-chain fatty acids. For the transfer of activated long-chain fatty acids across the inner mitochondrial membrane, acyl-CoA esters are transesterified to form acylcarnitines. Shortchain acylcarnitines

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in American Journal of Veterinary Research

few common exceptions (eg, flaxseed and canola oils), has favored increased consumption of vegetable oils with a high content of n-6 series polyunsaturated fatty acids relative to n-3 series polyunsaturated fatty acids. 4,5 Although beneficial when

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in American Journal of Veterinary Research

Analysis of serum FA concentrations was performed by use of gas chromatography. Fatty acids in serum samples were methylated by incubation with 10% methanolic HCl at 75°C for 2 hours. 26 Nonadecanoic acid was used as an internal standard. Samples (1 μL) of

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in American Journal of Veterinary Research

were greater in dogs fed diets restricted in fat or protein. Polyunsaturated fatty acids of the n-3 series may play a role in prevention and treatment of neoplastic disease. A study 13 in dogs with spontaneously occurring lymphoma revealed an

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in American Journal of Veterinary Research

Human clinical studies 1–6 and a recent meta-analysis 7 have found that dietary supplementation with fish oil and fish oil–derived fatty acids (in particular omega-3 fatty acids) provides benefits for patients with rheumatoid arthritis. Although

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in Journal of the American Veterinary Medical Association

resuspended in 0.5 mL of hexane that contained heptadecanoic acid (2 mg/mL) as an internal standard. Fatty acids were methylated with 10% methanolic HCl at 75°C for 1 hour. 32 Samples (1 μL) of FA methyl esters were injected into the gas chromatograph. f A

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in American Journal of Veterinary Research

Osteoarthritis has been estimated to affect up to 20% of dogs > 1 year of age. 1 Studies 2–8 have revealed that omega-3 fatty acids have beneficial effects in the treatment of rheumatoid arthritis. Furthermore, dietary supplementation with omega

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in Journal of the American Veterinary Medical Association

O mega-3 and omega-6 polyunsaturated fatty acids (PUFAs) are essential nutrients for horses. Omega-3 PUFAs include alpha-linolenic acid (ALA; 18:3n3), eicosapentaenoic acid (EPA; 20:5n3), docosapentaenoic acid (DPA; 22:5n3), and docosahexaenoic

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in Journal of the American Veterinary Medical Association