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and adult large animals is limited to antimicrobial and supportive therapy, with no interventions that specifically target cytokine removal. Plasma cytokine adsorption through a novel extracorporeal therapy device (CytoSorb; CytoSorbents Corp) has

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in American Journal of Veterinary Research

administration of ESWT was not significantly different from mean PVF after use of local anesthesia to eliminate the lameness would suggest that this change was clinically important. ABBREVIATIONS ESWT Extracorporeal shock wave therapy PVF Peak

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in Journal of the American Veterinary Medical Association

the lamellar tissue to LPS through extracorporeal perfusion of isolated equine limbs has been shown to induce pathological changes consistent with those of CHO-induced and naturally acquired laminitis. 22,23 The purpose of the study reported here was

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in American Journal of Veterinary Research

Extracorporeal shock wave therapy GAG Glycosaminoglycan OA Osteoarthritis PGE 2 Prostaglandin E 2 PSGAG Polysulfated glycosaminoglycan a. VersaTron, Sanuwave Inc, Alpharetta, Ga. b. Adequan IA, Luitpold Pharmaceuticals Inc, Shirley, NY. c

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in American Journal of Veterinary Research

Extracorporeal shock wave therapy is currently used in equine medicine to treat a wide variety of conditions. Although the exact method of action is unknown, it has been suggested that ESWT may have an effect on cell-to-cell interactions by

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in American Journal of Veterinary Research

–10 have shown little benefit to wound healing, although 1 study 3 did demonstrate that application of 1% silver sulfadiazine cream resulted in a faster rate of epithelialization. Extracorporeal shock wave therapy is a relatively new modality that has

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in Journal of the American Veterinary Medical Association

so far, no treatment has been completely successful. Therefore, development of a new, effective, and noninvasive treatment of distal limb wounds in horses would be extremely valuable. Extracorporeal shock wave therapy accelerates healing of chronic

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in American Journal of Veterinary Research

Extracorporeal shock wave therapy involves the focused application of shock waves. The high-energy shock waves are focused on a point distal to the applicator. 1 Radial pressure wave therapy involves deposition of lower-energy pressure waves on

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in American Journal of Veterinary Research

ESWT Extracorporeal shock wave therapy CPSD Chronic proximal suspensory desmitis MTIV Fourth metatarsal bone OSL-MC Origin of the suspensory ligament at the metacarpus SL Suspensory ligament RU Radiopharmaceutical uptake

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in American Journal of Veterinary Research

may have a positive impact on disease progression, allowing for management of lameness. Extracorporeal shock wave therapy has also been used to treat horses with osteoarthritis. 5,6 A report 6 involving a small number of clinical cases indicated

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in American Journal of Veterinary Research