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turtles specifically, a single prospective study has investigated one protocol in a related species with good success. In ornate box turtles ( Terrapene ornata ornata ), forelimb IM administration of dexmedetomidine-ketamine-midazolam (0.1, 10, and 1.0 mg

Open access
in American Journal of Veterinary Research

blood supply and infection. 2 , 4 Veterinary patients undergoing reconstructive procedures may require sedation for evaluation of their surgical site in the days and weeks following surgery. Dexmedetomidine, a common sedative medication, is a highly

Open access
in American Journal of Veterinary Research

analgesic effects. 1 The sedative effects are dose dependent, and onset has been reported as a median of 1 minute following IV administration and a median of 30 minutes following oral transmucosal administration in dogs. 2 Dexmedetomidine administration

Open access
in American Journal of Veterinary Research

opioids and NSAIDs in snakes, we recently investigated and demonstrated that dexmedetomidine, an α 2 -adrenoceptor agonist, is a candidate analgesic for ball pythons ( Python regius ). 18 α 2 -Adrenoceptor agonists are commonly used as an analgesic or

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in American Journal of Veterinary Research

extracapsular stabilization of the stifle joint. 16 A recent study 17 on humans revealed that intra-articular administration of dexmedetomidine enhanced postoperative pain relief, decreased the need for postoperative rescue analgesia, and prolonged the time

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in Journal of the American Veterinary Medical Association

Dexmedetomidine hydrochloride is a widely used α 2 -adrenoreceptor agonist that causes sedation, analgesia, decreased anesthetic requirements, and cardiovascular depression in cats. 1–3 The dextro enantiomer of medetomidine is responsible for the

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in American Journal of Veterinary Research

Dexmedetomidine is a synthetic α 2 -adrenoceptor agonist that is registered for use as a sedative-analgesic agent in veterinary medicine. Because it is a highly selective α 2 -adrenoceptor agonist, dexmedetomidine has been recommended for use as a

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in American Journal of Veterinary Research

Dexmedetomidine is an α 2 -adrenoceptor agonist commonly used in small animal practice to cause sedation and analgesia. 1–3 In a study 1 in cats, dexmedetomidine-mediated analgesia was short lasting and only evident after the administration of

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in American Journal of Veterinary Research

combination with ketamine induces reversible anesthesia in crocodiles, 15 alligators, 16 and chelonian species. 17,18 Similarly, dexmedetomidine combined with ketamine can induce anesthesia in chelonian species. 19–21 In 2 studies, 22,23 intrathecal

Full access
in American Journal of Veterinary Research

Dexmedetomidine is commonly administered to cats before anesthesia, primarily because of its reliable sedative, analgesic, and anesthetic-sparing effects. 1–3 However, dexmedetomidine can cause substantial cardiovascular effects and often results

Full access
in American Journal of Veterinary Research