A 6-year-old 23-kg intact male mixed-breed dog was presented to the Veterinary Teaching Hospital, University of Peradeniya, Sri Lanka, due to sudden blindness. Deworming and routine vaccinations of the dog were current.
difference in baseline patient characteristics. Randomization alone does not ensure an unbiased study. 1–7 The actual means by which data are collected will have a major impact on the validity of the results. 2–6
Blinding, which is withholding information
laparoscopic surgery, 4 blind percutaneous biopsy, and direct and indirect ultrasound-guided biopsy. Ultrasonography is also useful to visualize the echogenicity, size, and location of the liver. The abdomen is scanned for the presence of adequate liver tissue
the authors’ knowledge, the use of blind perineural injection techniques for ON or LCFN blockade by the sole use of SALMs in dogs has not been reported. In a previous study 16 in dogs, a relatively effective approach to block the SN by the use of an
previously reported cumulative incidence of IBK at the McNay farm (> 30%). 8 Vaccine efficacy was estimated as a risk ratio of 0.5 on the basis of the results of 3 randomized blinded trials identified in a systematic review 13 of IBK vaccine efficacy
This study was designed as a randomized, double-blinded, placebo-controlled crossover clinical trial. The study protocol was approved by the Institutional Animal Care and Use Committee of the University of California-Davis.
procedures complied with applicable Slovenian governmental regulations (Animal Protection Act, the Official Gazette of the Republic of Slovenia, 43/2007).
In a randomized, double-blinded, controlled trial, dogs with MMVD were randomly
Performed at the veterinary teaching hospital at Colorado State University from 2016 to 2017, the study was designed as a randomized blinded controlled clinical trial comparing the effect of CBD versus a placebo on seizure
investigator (RSC) was blinded to the treatment administered.
For each dog, after the assigned premedication was administered, an 18- or 20-gauge IV catheter was placed in one of the dog's cephalic veins. Anesthesia was induced with propofol (4 mg/kg, IV
is more likely to be beneficial rather than harmful, but the findings of the aforementioned retrospective study 17 challenge this notion and therefore prompted the design of a prospective, randomized, placebo-controlled, double-blinded clinical trial