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P rimates of the genus Papio (baboons) are kept in zoological collections and biomedical laboratories around the world and are frequently anesthetized for medical, scientific, and management reasons. However, we are unaware of any report in the

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in American Journal of Veterinary Research

Summary

A surgical method for obtaining transilial bone biopsy specimens in baboons that provides adequate amounts of trabecular and cortical bone for histomorphometric analysis was developed. Biopsy specimens were removed from a site on the craniodorsal portion of the ilium by use of an 8-mm trephine.

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in Journal of the American Veterinary Medical Association

Summary

This study establishes preliminary pharmacokinetic data on the use of gentamicin sulfate administered im to baboons. Serum concentrations ≥ 12 μg/ml are generally agreed to cause toxicosis in human beings. On the basis of preliminary test results suggesting that the manufacturer's recommended dosage for dogs of 4.4 mg/kg of body weight caused potentially toxic serum concentrations, a dosage of 3 mg/kg was chosen to conduct a single-dose kinetic study in 6 baboons. Using a single-compartment model, the gentamicin serum half-life for im administration of 3 mg of gentamicin/kg was 1.58 hours, and serum concentrations remained below the potentially toxic concentrations reported for human beings. We suggest that a dosage of 3 mg/kg is safer than a dosage of 4.4 mg/kg administered im to baboons. Minimal inhibitory concentrations for 2 Pseudomonas aeruginosa isolates were ≤ 1 μg/ml. On the basis of our measured elimination half-life of 1.58 hours, it is reasonable to suppose that dosing q 24 h will be inadequate to maintain therapeutic serum concentrations. We calculate that serum concentrations will remain at or above our measured minimal inhibitory concentration for P aeruginosa (1 μg/ml) for 100% of the treatment time if the animal is dosed q 6 h, 78% for dosing q 8 h, and 52% for dosing q 12 h. Therefore, we suggest 3 mg/kg, q 8 h or q 6 h as appropriate dosing schedules for the use of gentamicin sulfate administered im to baboons.

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in American Journal of Veterinary Research

of hamadryas baboons ( Papio hamadryas ) and the other housing a pair of Debrazza's monkeys ( Cercopithecus neglectus ). No other primates had signs of illness at the time of evaluation of the colobus monkey. Various other mammal, bird, and reptile

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in Journal of the American Veterinary Medical Association

History A 6-year-old female baboon was a part of a cohort of 12 female baboons purchased from a biomedical research institution. a The baboon had been born at the institution. The cohort arrived at the Mayo Clinic, Rochester, Minn, in

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in Journal of the American Veterinary Medical Association

virus from a nearby colony of baboons, the natural host of HVP-2. Herpesvirus papio2 infection should be considered in the differential diagnosis for acute encephalopathy in primate monkeys and humans, particularly following exposure to baboons. See

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in Journal of the American Veterinary Medical Association

and that high concentrations of DHA and AA do not harm or benefit the development of visual function in 4-month-old animals. A close, linear correlation between retinal DHA status and a-wave variables has been detected in preterm baboon fetuses. 55

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in Journal of the American Veterinary Medical Association

Spontaneous endometriosis has been reported in multiple nonhuman primate species, including, most commonly, macaques and baboons. 1,2 Prevalence rates as high as 30% have been reported in female macaques from several institutions, 3–5 making

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in Journal of the American Veterinary Medical Association

been identified in baboons, 10 rainbow trout, 11 and laboratory cats. 8 Noxious stimuli, such as an electric shock or a loud noise, may elicit an attack against a nearby animal or an object primarily when the escape-avoidance behavior is not possible

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in Journal of the American Veterinary Medical Association

, papilledema is a qualitative rather than a quantitative clinical finding. Magnetic resonance imaging has been used in humans and baboons to noninvasively measure ICP. 5 Little data exist to aid the assessment of ICP in dogs with an intracranial mass. Venous

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in American Journal of Veterinary Research