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compared to baseline. Figure 1 Leukocyte concentrations before (T0) and 7, 14, and 21 days (T7, T14, and T21) after administration of firocoxib and phenylbutazone. APS = Autologous protein solution. F = Firocoxib. P = Phenylbutazone. PRP = Platelet

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in American Journal of Veterinary Research

Autologous protein solution (APS) and platelet-rich plasma (PRP) are 2 such autologous blood-based therapies for which there is supporting evidence for their role in reducing pain and improving the quality of healing in musculoskeletal disease (osteoarthritis

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point-of-care treatment options of PRP. Autologous protein solution is a therapeutic blood product designed to achieve these goals and is created in a 2-step process. Blood is first processed in an APS separator, c which sequesters WBCs and platelets

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in American Journal of Veterinary Research

effective at reducing joint inflammation and pain. These effects of regenerative therapies will be described in greater detail in this paper. Examples of hemoderivative regenerative therapies include PRP, ACS, autologous protein solution (APS), and α-2

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in Journal of the American Veterinary Medical Association

osteoarthritis treated with an autologous protein solution. 16 In the study reported here, as in any study, it was difficult, if not impossible, to control the amount of exercise (jogging) from one horse to the next within an experiment. First, not all horses

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in American Journal of Veterinary Research

MJ . A comparative review of autologous conditioned serum and autologous protein solution for treatment of osteoarthritis in horses . Front Vet Sci . 2021 ; 8 : 82 . doi: 10.3389/FVETS.2021.602978/BIBTEX 14. da Silva Xavier AA , da Rosa PP

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in American Journal of Veterinary Research

were also obtained in a study 38 of dogs that had single-limb lameness because of osteoarthritis in a stifle or elbow joint and that received an intra-articular injection of autologous protein solution or saline solution (control group) in the affected

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in American Journal of Veterinary Research

-articular injection of autologous protein solution for treatment of osteoarthritis in horses . Am J Vet Res . 2014 ; 75 ( 2 ): 141 – 151 . doi: 10.2460/ajvr.75.2.141 4. Linardi RL , Dodson ME , Moss KL , King WJ , Ortved KF . The effect of

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in Journal of the American Veterinary Medical Association

. Therapeutic potential of platelet-rich plasma in canine medicine . Arch Razi Inst . 2021 ; 76 ( 4 ): 721 - 730 . doi: 10.22092/ari.2021.355953.1749 10. King W , Cawood K , Bookmiller M . The use of autologous protein solution (Pro-Stride®) and

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in Journal of the American Veterinary Medical Association

.12015.x 14. Bertone AL , Ishihara A , Zekas LJ , et al. Evaluation of a single intra-articular injection of autologous protein solution for treatment of osteoarthritis in horses . Am J Vet Res 2014 ; 75 : 141 – 151 . 10.2460/ajvr.75

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in American Journal of Veterinary Research