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has increased in veterinary medicine since its development in 2011 and FDA approval in dogs and cats. The FDA-approved product Nocita has been approved for a single dose by infiltration injection at the time of incisional closure of cranial cruciate

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in Journal of the American Veterinary Medical Association

injection is a subcutaneous line block of bupivacaine at the closure of surgery. Bupivacaine liposome injectable suspensions (BLIS) have become a popular choice for longer-lasting local analgesia following soft tissue and orthopedic surgeries. Nocita (Elanco

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in Journal of the American Veterinary Medical Association

bupivacaine liposome injectable suspension (BLIS; Nocita) is FDA approved for single-dose infiltration into the surgical site to provide local postoperative analgesia for cranial cruciate ligament surgery in dogs and as a peripheral nerve block to provide

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in Journal of the American Veterinary Medical Association

lasting for 14 (6 to 24) hours 3 . Additives, such as dexamethasone or dexmedetomidine, have failed to reliably extend the duration of the analgesic effect of bupivacaine beyond 24 hours. 4 – 7 Bupivacaine liposome injectable suspension (Nocita; Aratana

Open access
in American Journal of Veterinary Research
Open access
in American Journal of Veterinary Research

block of horses was treated with either BHCl (Marcaine; Hospira Inc; 7.5 mg of BHC1/mL) or LB (Nocita; Aratana Therapetics Inc; 13.3 mg of BL/mL), and following a 7-day washout period, the opposite treatment was performed on the contralateral limb

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in American Journal of Veterinary Research
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, Evaluation of injection volumes for the transversus abdominis plane block in dog cadavers: a preliminary trial. Vet Anaesth Analg . 2021 ; 48 ( 1 ): 142 – 146 . 33257280 28. Elanco . Package insert . Nocita ; 2021 . Accessed August 1, 2022 . https://www.elancolabels.com/us/nocita

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in Journal of the American Veterinary Medical Association

. The bladder was leak tested and the surgical site lavaged with saline and suctioned prior to routine closure of the bladder and abdominal wall. Nocita (5.3 mg/kg, SC, once) was administered along the incision site. Postoperative analgesia after both

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in Journal of the American Veterinary Medical Association

-encapsulated bupivacaine MpE Morphine equivalents PNT Pressure nociceptive threshold TPLO Tibial plateau leveling osteotomy Footnotes a. Randomization Plans. Available at: gdallal.pages.tufts.edu/assign.htm . Accessed Oct 10, 2019. b. Nocita, Aratana

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in Journal of the American Veterinary Medical Association

in people. 14 , 15 A veterinary formulation of liposomal bupivacaine (NOCITA) is now also available. Studies of dogs undergoing stifle surgery found that this product provided local analgesia for 72 hours postoperatively and lowered the incidence of

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in Journal of the American Veterinary Medical Association