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antiinflammatory drug (NSAID), especially phenylbutazone (PBZ). 3 This putative pharmacological risk and the consistent predilection site in the right dorsal colon (RDC) could provide clues to the management of right dorsal colitis. Diagnosis is usually

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in American Journal of Veterinary Research

Phenylbutazone and flunixin meglumine are the 2 NSAIDs most commonly used in horses to reduce inflammation and pain associated with lameness. There is little controversy concerning their use for this purpose. However, they are also sometimes

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in American Journal of Veterinary Research

Nonsteroidal anti-inflammatory drugs are highly effective for the treatment of a variety of common diseases in horses, including degenerative joint disease and colic. 1,2 The anti-inflammatory properties of NSAIDs are a result of COX inhibition

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in Journal of the American Veterinary Medical Association

– 11 NSAIDs have been shown in both horses and humans in vivo to affect the concentrations of some cytokines and growth factors in blood-derived autologous substances such as PRP. 12 – 14 Based on this, it is possible that the administration of

Open access
in American Journal of Veterinary Research

The NSAIDs are used in a number of settings in veterinary medicine to control acute and chronic pain and inflammation. Most commonly, NSAIDs are used for managing chronic pain associated with osteoarthritis and acute pain associated with surgical

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in American Journal of Veterinary Research

Introduction NSAIDs are commonly used in equine practice to treat pain, inflammation, and fever. Effects of NSAIDs are mediated by inhibition of the cyclooxygenase (COX) cascade, which consists of 2 isoforms, COX-1 and COX-2. NSAIDs have

Open access
in Journal of the American Veterinary Medical Association

Nonsteroidal anti-inflammatory drugs are commonly used to alleviate clinical signs associated with orthopedic diseases; however, the effect of NSAIDs on the progression of osteoarthritis remains controversial. Evidence suggests that NSAIDs

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in American Journal of Veterinary Research

Nonsteroidal anti-inflammatory drugs are widely used by horse owners, trainers, and veterinarians. The practice of combining NSAIDs has been empirically used to enhance the analgesic properties of these drugs in performance horses. The effect of

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in American Journal of Veterinary Research

In veterinary medicine, the use of NSAIDs for treatment of pain is increasing. 1 Once administered primarily to dogs with osteoarthritis to reduce joint pain and decrease synovitis, NSAIDs are now frequently used to control postoperative pain and

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in American Journal of Veterinary Research

size, tumor location, presence of serosal extension, presence of lymphatic invasion, completeness of surgical margins, and presence of metastasis. The details of adjuvant chemotherapy and NSAID administration were recorded when available. Follow-up data

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in Journal of the American Veterinary Medical Association