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B ovine respiratory disease (BRD) continues to cause major economic losses for the beef cattle industry in the US 1 , 2 and is recognized as the leading cause of death of beef calves. 3 , 4 Bovine respiratory syncytial virus (BRSV) is one of the

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in American Journal of Veterinary Research
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in American Journal of Veterinary Research
in American Journal of Veterinary Research

respiratory syncytial virus, BRSV is an important respiratory pathogen that can cause severe disease in naive cattle of all ages, but primarily affects young cattle in recurrent seasonal outbreaks. 1–4 Clinical disease in cattle is characterized by pyrexia

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in Journal of the American Veterinary Medical Association

Calfhood pneumonia incited by acutely infecting viruses such as BRSV continues to be a major clinical and economic problem in cattle-rearing operations. 1,2 There has been little improvement in the morbidity and mortality rates associated with

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in Journal of the American Veterinary Medical Association

occurs when passive immunity has waned and is characterized by pyrexia, coughing, and tachypnea, often progressing rapidly to dyspnea. 4 The efficacy of parenteral administration of several commercially available modified-live and inactivated BRSV

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in Journal of the American Veterinary Medical Association

Bovine respiratory syncytial virus is a single-stranded negative-sense RNA virus in the family Paramyxoviridae . In young calves, BRSV infection causes moderate to severe disease characterized by bronchitis, bronchiolitis, and interstitial

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in American Journal of Veterinary Research

disease. Moreover, exposure of cattle to environmental antigenic inhalants is an unavoidable consequence of housing conditions. In other studies 4,5 conducted by our laboratory group, there was an increase in disease severity in calves infected with BRSV

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in American Journal of Veterinary Research

antibodies via colostrum as soon as possible after birth to protect it against disease until its own immune system can mature. Maternal antibodies help protect neonatal calves against clinical disease caused by BRSV, 1–3 BVDV, 1,4,5 BHV1, 6 PI3, 7 BCV 4

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in American Journal of Veterinary Research

2, BRSV, and PI3V at weaning between calves that received an initial, or priming, dose of the same or similar MLV vaccine via SC or IN administration while they had maternal antibodies against those pathogens. To assess the effects of age and route

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in American Journal of Veterinary Research