Case Description—2 dogs and 5 cats were evaluated for treatment of ureteroliths.
Clinical Findings—Spontaneous retrograde movement of 1 or more ureteroliths was detected by radiography, ultrasonography, fluoroscopy, and a combination of fluoroscopy and ultrasonography. The ureteroliths moved retrograde up to 4 centimeters. Retrograde movement of ureteroliths into the renal pelvis resulted in improved renal function in some patients but made complete surgical removal of all uroliths more difficult.
Treatment and Outcome—Medical management was not successful, and ureteroliths were surgically removed. Surgical management of ureteroliths was complicated by retrograde movement of ureteroliths in the perioperative period.
Clinical Relevance—Ureteroliths can move retrograde within the ureter and even back into the renal pelvis. Retrograde movement of ureteroliths may make surgical planning more difficult.
Objective—To evaluate adrenal sex hormone concentrations
in response to ACTH stimulation in healthy
dogs, dogs with adrenal tumors, and dogs with pituitary-
dependent hyperadrenocorticism (PDH).
Animals—11 healthy control dogs, 9 dogs with
adrenal-dependent hyperadrenocorticism (adenocarcinoma
[ACA] or other tumor); 11 dogs with PDH, and
6 dogs with noncortisol-secreting adrenal tumors
Procedure—Hyperadrenocorticism was diagnosed on
the basis of clinical signs; physical examination findings;
and results of ACTH stimulation test, low-dose
dexamethasone suppression test, or both. Dogs with
noncortisol-secreting ATs did not have hyperadrenocorticism
but had ultrasonographic evidence of an AT.
Concentrations of cortisol, androstenedione, estradiol,
progesterone, testosterone, and 17-hydroxyprogesterone
were measured before and 1 hour after IM
administration of 0.25 mg of synthetic ACTH.
Results—All dogs with ACA, 10 dogs with PDH, and
4 dogs with ATs had 1 or more sex hormone concentrations
greater than the reference range after ACTH
stimulation. The absolute difference for progesterone,
17-hydroxyprogesterone, and testosterone concentrations
(value obtained after ACTH administration minus
value obtained before ACTH administration) was significantly
greater for dogs with ACA, compared with
the other 3 groups. The absolute difference for
androstenedione was significantly greater for dogs
with ACA, compared with dogs with AT and healthy
Conclusions and Clinical Relevance—Dogs with
ACA secrete increased concentrations of adrenal sex
hormones, compared with dogs with PDH, noncortisol-secreting ATs, and healthy dogs. Dogs with noncortisol-secreting ATs also have increased concentrations of sex hormones. There is great interdog variability
in sex hormone concentrations in dogs with ACA
after stimulation with ACTH. (J Am Vet Med Assoc
Objective—To determine clinical, radiographic, and
histologic abnormalities in adult cats > 1 year old with
spontaneous (ie, nontraumatic) femoral capital physeal
Procedure—Medical records of cats > 1 year old with
femoral capital physeal fractures and no history of
trauma were examined.
Results—Mean ± SD age of the cats was 22.5 ± 6.5
months. Twenty-five cats were neutered males. Mean
weight of the cats was significantly greater than mean
weight of a group of age- and sex-matched control cats.
Of 16 cats for which age at the time of neutering was
known, 14 had been neutered before 6 months of age.
Nine cats had bilateral fractures. Severity of femoral
neck osteolysis and sclerosis increased with increased
duration of clinical signs. The contralateral femoral capital
physis, distal femoral physes, and proximal tibial
physes were radiographically open in 13 of 18, 19 of 24,
and 24 of 24 cats, respectively. Histologically, the epiphysis
contained normal articular cartilage and bone,
but attached growth plate cartilage lacked the normal
columnar arrangement of chondrocytes.
Conclusions and Clinical Relevance—Results suggested
that adult cats with spontaneous femoral
capital physeal fractures were most likely to be
heavier, neutered males with delayed physeal closure.
(J Am Vet Med Assoc 2002;221:1731–1736)