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  • Author or Editor: Richard Dorn x
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in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association

Summary

The purpose of this study was to document the effect of calfhood vaccination for Mycobacterium paratuberculosis on a serologic elisa. Fifteen calves vaccinated with a killed paratuherculosis vaccine and 5 unvaccinated control calves were tested from the first through the fifteenth month of life. Age of vaccination ranged from 5 to 40 days. Blood samples were collected prior to vaccination and periodically thereafter. Serum antibody was analyzed by use of the elisa. All calves were elisa-negative prior to vaccination. Thirteen of 15 vaccinated calves became elisapositive between 2 and 6 months after vaccination. The unvaccinated cohort remained elisa-negative. Widespread use of vaccine may interfere with diagnosis of paratuberculosis and with control programs that are based 0n serologic tests that measure humoral antibody.

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in American Journal of Veterinary Research