Objective—To determine the prevalence of systemic
hypertension in cats with diabetes mellitus and establish
ranges for echocardiographic variables in diabetic
Animals—14 cats with diabetes mellitus and 19
healthy control cats.
Procedure—Systolic blood pressure was measured
indirectly with a noninvasive Doppler technique.
Ophthalmic and echocardiographic examinations
were performed, and urine protein concentration was
measured. Cats were considered to have hypertension
if they had systolic blood pressure > 180 mm Hg
and at least 1 other clinical abnormality typically associated
with hypertension (eg, hypertensive retinopathy,
left ventricular hypertrophy, or proteinuria).
Results—None of the diabetic or control cats had
systolic blood pressure > 180 mm Hg. One diabetic
cat had left ventricular hypertrophy, but systolic blood
pressure was 174 mm Hg. None of the cats had evidence
of hypertensive retinopathy or proteinuria.
Mean values for echocardiographic variables for the
diabetic cats were not significantly different from published
values for healthy cats.
Conclusions and Clinical Relevance—Results suggest
that hypertension does not occur or occurs in
only a small percentage of cats with diabetes mellitus.
(J Am Vet Med Assoc 2003;223:198–201)
Objective—To determine whether conscious, unsedated
cats will inhale a nebulized material administered
via a facemask and whether this material will
reach the lower airways.
Animals—20 healthy adult cats.
Procedure—Technetium Tc 99m-diaminetriaminopentaacetic
acid (99mTc-DTPA) was nebulized into a spacer
and administered to the cats via a closely fitting facemask.
By use of a gamma camera, images were then
immediately obtained to determine the distribution of
99mTc-DTPA within the lower airways.
Results—Images obtained by use of the gamma
camera revealed that all 20 cats had inhaled 99mTc-DTPA from the facemask. In each cat, deposition of
the radiopharmaceutical agent was evident throughout
the lung fields.
Conclusions and Clinical Relevance—Awake cats
that were not used to the application of a facemask
did inhale substances from such a device.
Aerosolization of medications may be a feasible route
of administration for cats with lower airway disease.
(Am J Vet Res 2004;65:806–809)
Objective—To evaluate the clinicopathologic features, response to treatment, and risk factors associated with idiopathic neutropenia in dogs.
Design—Retrospective case series.
Procedures—Medical records of dogs with idiopathic neutropenia were reviewed. Signalment, history, clinical signs, and response to treatment were recorded and compared with that in dogs with neutropenia attributable to known causes and to dogs without neutropenia (controls).
Results—Compared with dogs with neutropenia attributable to known causes, dogs with idiopathic neutropenia had lower neutrophil counts and were younger. When compared with control dogs, age < 4 years was identified as a risk factor for developing idiopathic neutropenia. In all dogs with idiopathic neutropenia, remission of neutropenia occurred within 18 days after administration of prednisone (2 to 4 mg/kg [0.9 to 1.8 mg/lb], PO, daily) and no serious complications or infections developed.
Conclusions and Clinical Relevance—An immunemediated pathogenesis should be considered for dogs with idiopathic neutropenia in which the cause is not known. Severe neutropenia and young age were significantly associated with idiopathic neutropenia in dogs. Prognosis appeared to be excellent with prednisone treatment.