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  • Author or Editor: Paula A. Schaffer x
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History

An adult 3.7-kg (8.1-lb) neutered male domestic longhair cat was evaluated at the Eagle Valley Pet Hospital because of lethargy and lameness of the left forelimb of approximately 1 week's duration.

Clinical and Gross Findings

The soft tissues of multiple digits on all 4 paws were very firm and severely thickened up to 2 times their expected dimensions. There was ulceration and thick serocellular crusting around the nail beds of affected digits, which were discolored dark red to purple. A CBC revealed leukocytosis (WBC count, 22,700 WBCs/μL; reference range, 4,200 to 15,600 WBCs/μL) with neutrophilia (17,933 neutrophils/μL; reference range,

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in Journal of the American Veterinary Medical Association
History

A 6-month-old 25.5-kg (56.1-lb) spayed female Labrador Retriever was evaluated because of hematuria and hyporexia of 4 days' duration. Palpation of the dog's abdomen elicited signs of pain. Urinalysis revealed urine specific gravity of 1.011 with 3+ proteinuria, 4+ hematuria, and 1+ pyuria on a dipstick and a few bacteria. Treatment of the dog with cefpodoxime and carprofen for suspected urinary tract infection was initiated. Despite treatment, the dog's clinical signs persisted and over the next 2 days worsened to include stranguria, dysuria, and pollakiuria. The dog was referred to a specialty clinic.

Clinical and Clinicopathologic Findings

Clinicopathologic analyses

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in Journal of the American Veterinary Medical Association

Abstract

Objective—To identify epidemiological trends in cutaneous neoplasms affecting equids in central North America and compare them with previously reported trends.

Design—Retrospective case series.

Sample—3,351 cutaneous biopsy specimens from 3,272 equids with a neoplastic diagnosis.

Procedures—Diagnostic reports from 2 diagnostic laboratories (Colorado State University and Prairie Diagnostic Services Inc) were reviewed for frequency of specific lesions and epidemiological trends. Variables included in analyses (if known) were age, sex, breed, geographic location, date of diagnosis, location of neoplasm on the body, and presence or absence of ulceration.

Results—Sarcoid, squamous cell carcinoma (SCC), and melanoma were the 3 most common tumors diagnosed. Tumors associated with UV radiation (SCC, SCC in situ, hemangioma, hemangiosarcoma) were 2.3 (95% confidence interval [CI], 1.8 to 3.0) times as common in biopsy specimens received by Colorado State University than in specimens received by Prairie Diagnostic Services Inc. Appaloosa horses and American Paint horses, respectively, were 7.2 (95% CI, 5.6 to 9.2) and 4.4 (95% CI, 3.6 to 5.4) times as likely as other breeds to have tumors associated with UV radiation. Thoroughbreds were predisposed to cutaneous lymphoma, whereas Arabians were more likely to have melanomas. Draft and pony breeds were 3.1 (95% CI, 1.9 to 5.1) times as likely as other breeds to have benign soft tissue tumors. Morgans and pony breeds more commonly had basal cell tumors. Tumors in the perianal region were significantly more likely to be SCC or melanoma while tumors on the limbs were more likely to be giant cell tumor of soft parts.

Conclusions and Clinical Relevance—Signalment, anatomic location of the mass, and geographic location of the horse can be used to help equine practitioners formulate differential diagnoses for cutaneous masses. Further research is necessary to identify the biological basis for the development of many equine cutaneous neoplasms.

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in Journal of the American Veterinary Medical Association