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Abstract

Objective—To evaluate the effect of renal autograft ischemia and reperfusion associated with renal transplantation on pulse rate and pressure and arterial blood pressure variables in clinically normal cats.

Animals—10 cats.

Procedures—A radiotelemetric implant was placed in each cat to measure hemodynamic variables; baseline data were recorded before surgery. Standard heterotopic renal implantation and contralateral nephrectomy were performed (day 0). Autografts were stored in cold sucrose phosphate solution for 30 minutes (n = 5) or 3 hours (5); cats were anephric during this period. Hemodynamic variables were recorded every 5 minutes for up to 16 days after surgery; mean daily values were calculated.

Results—Data from 6 cats were available for analysis. Two cats developed ureteral obstructions and became azotemic at 111 and 197 hours after kidney reperfusion. Mean serum creatinine and BUN concentrations were greater than baseline values on days 1 and 2. Although changes from baseline hemodynamic values were detected in some cats, arterial blood pressure measurements did not change significantly from baseline at any time point. Compared with baseline data, mean pulse rate was increased on days 1 and 2 and days 6 through 12; mean pulse pressure was increased on days 1 and 2.

Conclusions and Clinical Relevance—In clinically normal cats, hypertension was not induced by clinically relevant periods of ischemia-reperfusion injury of renal autografts and was not an inherent consequence of the transplantation process. Causes of marked posttransplantation hypertension in cats with chronic kidney disease require further investigation.

Full access
in American Journal of Veterinary Research

Abstract

Objective—To describe complications associated with use of a subcutaneous vascular access port (SVAP) in cats and dogs treated with fractionated radiotherapy and to determine predisposing factors for developing these complications.

Design—Retrospective case series.

Animals—46 cats and 126 dogs.

Procedures—The medical records of cats and dogs undergoing radiation therapy that received placement of an SVAP between March 1996 and August 2007 were reviewed. Data were recorded and analyzed to determine factors for development of complications associated with the use of an SVAP during treatment with fractionated radiotherapy.

Results—18 and 36 major and minor complications were identified, respectively. Sex and the lack of administration of propofol during anesthesia induction were significantly associated with development of major complications. Female cats and dogs were 5.00 times as likely as male cats and dogs to develop major complications associated with SVAP usage. Animals in which propofol was not administered were 19.15 times as likely as animals administered propofol to develop major complications. Placement of SVAP catheters in a femoral vein was 17.20 times as likely as placement in the jugular vein to result in minor complications.

Conclusions and Clinical Relevance—Factors associated with the development of complications included sex, propofol administration, and vein in which an SVAP catheter was inserted. The use of an SVAP may be a useful alternative to repeated catheterizations in cats and dogs.

Full access
in Journal of the American Veterinary Medical Association

Abstract

OBJECTIVE To determine which method (lateral fabellotibial suture [LFS], tibial plateau leveling osteotomy [TPLO], tibial tuberosity advancement [TTA], or tightrope-like braided multifilament suture secured with metallic buttons [TR]) Veterinary Orthopedic Society (VOS) members preferred for treating cranial cruciate ligament rupture (CCLR) in dogs weighing > 15 kg (33 lb), identify factors associated with this preference, and assess concerns related to surgical implant material used.

DESIGN Cross-sectional study.

SAMPLE 187 VOS members.

PROCEDURES All registered VOS members received an online survey from June to July 2016. Responses were compiled and evaluated for associations with method preferences and perceived complications.

RESULTS Overall response rate was 38.4% (221/575). Respondents had graduated from veterinary school a mean of 23 years prior to survey completion, and collectively they performed approximately 30,000 CCLR surgeries annually. The most commonly preferred method was TPLO (147 [78.6%]), followed by TTA (26 [13.9%]), the LFS procedure (11 [5.9%]), and the TR procedure (3 [1.6%]). The preference for TPLO was independent of board certification or college of training (American, European, or other College of Veterinary Surgeons). Non-board-certified surgeons, including general practitioners, also favored TPLO. The most common perceptions were that titanium implants (used for TTA) were associated with the lowest incidence of major complications, whereas braided multifilament suture (used for the TR procedure) was associated with the highest incidence of major complications.

CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that TPLO was preferred for treating CCLR in dogs weighing > 15 kg and that the TR procedure was perceived as having the highest complication rate. With results of this survey in mind, use of the TR procedure should be considered cautiously when treating CCLR.

Full access
in Journal of the American Veterinary Medical Association