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  • Author or Editor: Marileda Carvalho x
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Abstract

Objective

To evaluate the reliability of urine carnitine concentrations measured in single postprandial samples, compared with carnitine concentrations measured in 24-hour urine samples.

Animals

19 healthy Beagles.

Procedure

After emptying the urinary bladder by catheterization, dogs were fed a canned canine maintenance diet. Approximately 8 hours later, urine, plasma, and serum samples were obtained for determination of urinary carnitine fractional excretion and urine carnitine-to-creatinine concentration ratio. Results were compared with 24-hour urinary carnitine excretion rate.

Results

Fractional excretion of carnitine and urine carnitine-to-creatinine ratios correlated poorly with 24-hour urinary carnitine excretion.

Conclusion

Determination of 24-hour urinary carnitine excretion is recommended to measure urine carnitine concentrations in dogs. (Am J Vet Res 1996;57: 1185-1188)

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in American Journal of Veterinary Research