Objective—To determine whether findings of urinalyses
could be used to reliably distinguish gonadectomized
cats with urine-marking behavior from those
with no problem urination.
Design—Case control study.
Animals—58 gonadectomized cats (47 males and 11
females) with urine-marking behavior (ie, marking of
vertical surfaces) and 39 (26 males and 13 females)
without problem urination or urinary tract-associated
Procedure—Urine was collected by cystocentesis
from all cats. Findings of urinalyses of cats with urinemarking
behavior were analyzed statistically for sexrelated
differences and differences between cats that
marked vertical surfaces only and those that marked
both vertical and horizontal surfaces; findings of urinalyses
of control cats were compared between
sexes. Subsequently, results of urinalyses of cats
with urine-marking behavior were compared with
those of control cats.
Results—With regard to variables measured via urinalysis,
there were no differences between male and
female cats within either group. Among cats with
urine-marking behavior, there were no differences
between those that only marked vertically and those
that marked vertically and horizontally. Analyses of
data from all cats with urine-marking behavior and
control cats revealed no differences that could be
associated with urine marking.
Conclusions and Clinical Relevance—These data
suggest that urine-marking behavior by gonadectomized
cats is an aspect of normal behavior. Clinicians
are advised to focus on behavioral history of house-soiling
cats to differentiate between urine-marking behavior
and inappropriate urination; for the latter, urinalysis
is appropriate to rule out lower urinary tract disorders.
(J Am Vet Med Assoc 2003;223:457–461)