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A 2-day-old 44-kg (97-lb) purebred female Holstein calf was evaluated for weakness, signs of depression, and inability to stand unsupported. Immediately after birth, the calf could stand and was tube fed with approximately 4 L of colostrum. Twenty-four hours after birth, the calf was standing and suckled its daily requirement of milk replacer, but 48 hours after birth, the calf was recumbent and only drank half of its 2-L morning milk replacer feeding. The owner had treated the calf with 100 mg of tulathromycin that morning. On initial examination, rectal temperature (39°C [101.5°F]) and heart rate (120 beats/min) were

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in Journal of the American Veterinary Medical Association
History

A 7-day-old 40-kg mixed-breed beef heifer calf was presented for recheck evaluation because of persistent signs of inspiratory dyspnea. Four days earlier, the calf had been examined because of labored breathing with marked abdominal effort that developed after the calf (unwitnessed birth) had been kicked and appeared rejected by its dam; was deemed to have had a clinically normal body temperature, pulse, and behavior and no obvious signs of dysmaturity or congenital defects; and then tube fed 2 L of colostrum harvested from its dam. During the initial examination 4 days earlier, the calf was febrile (rectal temperature unknown),

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in Journal of the American Veterinary Medical Association