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- Author or Editor: Klaus Doll x
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Abstract
Objective—To compare results obtained by use of laparoscopyassisted abomasopexy versus omentopexy via right flank laparotomy for the treatment of dairy cows with left displaced abomasum (LDA).
Animals—120 dairy cows with an LDA.
Procedure—In a prospective clinical trial, cows were randomly allocated to the abomasopexy group (laparoscopy-assisted abomasopexy) or to the control group (omentopexy via right flank). Data were obtained during the first 5 days after surgery and 6 weeks and 6 months after surgery.
Results—59 of 60 cows in the abomasopexy group and all 60 cows in the control group were treated successfully. Median duration was shorter for the laparoscopic procedure (27.5 minutes), compared with that for the control group (38 minutes). Five cows in the abomasopexy group had wound complications and 2 had LDA relapses, compared with 2 wound complications and no relapses in the control group. During the 5 days after surgery, the abomasopexy group had a significantly higher increase in rate of energy intake and milk yield and a more rapid return to reference range for serum glutamic dehydrogenase activity and total bilirubin concentration, compared with results for the control group.
Conclusions and Clinical Relevance—Success rates were almost equal for both methods. Advantages of the laparoscopic abomasopexy procedure include practicality, low risk of complications, and rapid postoperative recovery. Contraindications are cardiopulmonary diseases. Other disadvantages include the cost of the instruments and inability to perform the procedure in cows with abomasal adhesions.
Abstract
Objective—To compare the content of substance P, vasoactive intestinal polypeptide, and neurofilament 200 in biopsy specimens taken from the abomasal wall of healthy cows of 2 breeds.
Sample Population—Biopsy specimens taken from different sites of the abomasal wall from 20 German Holstein cows and 20 German Fleckvieh cows.
Procedures—Biopsy specimens were examined immunohistochemically, and the content of substance P, vasoactive intestinal polypeptide, and neurofilament 200 was determined by measuring the immunoreactive areas.
Results—Significant differences between the breeds were detected. Substance P-immuno-reactive area in the corpus abomasi was significantly smaller in the German Holsteins (geometric mean ± geometric SD, 679 ± 1.83 μm2) than in the German Fleckvieh cows (1,020 ± 1.65 μm2). Concerning vasoactive intestinal polypeptide, differences between breeds were not significant. Overall nerve density in the antral abomasal wall was significantly greater in German Holsteins than in German Fleckvieh cows (immunoreactive areas for neurofilament 200 in German Holsteins was 4,842 ± 1.29 μm2 and in German Fleckvieh cows was 3,333 ± 1.63 μm2).
Conclusions and Clinical Relevance—The significantly lower content of substance P in the corpus abomasi could explain why German Holstein cows are predisposed to abomasal displacement, compared with German Fleckvieh cows, in which this disease is a rare finding.
Abstract
Objective—To determine the correlation between insulin concentrations and myoelectrical activity of the abomasum in cows with a left displaced abomasum (LDA).
Animals—14 dairy cows with an LDA at the onset of lactation.
Procedure—During surgical correction of an LDA, 3 pairs of electrodes were placed in the smooth muscle of the gastrointestinal tract (abomasal body, pars pylorica, and duodenum) of each cow. Electromyographic recordings were obtained once per day for 7 days. Samples were collected and tested to determine concentrations of insulin, glucagon, cortisol, glucose, β-hydroxybutyrate, and nonesterified fatty acids.
Results—All 14 cattle had high glucose and insulin concentrations at the time of admission, independent of ketosis. Concentrations of glucose and insulin decreased slowly after surgical treatment and were associated with a progressive increase in abomasoduodenal myoelectric activity. The 14 cows were allocated into 2 groups (suspected insulinresistant cattle, n = 7; suspected non–insulin-resistant cattle, 7) on the basis of persistent hyperinsulinemia during the postoperative period. Seven days after surgery, the abomasoduodenal myoelectric patterns were still significantly lower for the insulinresistant cows, compared with patterns for the non–insulin-resistant cows.
Conclusions and Clinical Relevance—Insulin resistance appears to be common in cows with an LDA. Analysis of results of this study reveals that abomasal atony in cows with an LDA depends on persistence of high serum concentrations of insulin. Results of this study could provide an explanation for a pathogenetic factor of LDAs and the frequent relapses of cattle affected by this condition. (Am J Vet Res 2004;65:1319–1324)
