Objective—To determine outcome for equids with cutaneous neoplasms treated with cisplatin-containing biodegradable beads, alone or in conjunction with debulking.
Design—Retrospective case series.
Animals—56 horses, 1 zebra, 1 donkey, and 1 mule.
Procedures—Medical records were reviewed. Follow-up information was obtained through telephone conversations with owners and trainers of the animals.
Results—22 tumors were sarcoids, 6 were fibrosarcomas, 1 was a fibroma, 2 were peripheral nerve sheath tumors, 11 were squamous cell carcinomas, 14 were melanomas (13 gray horses and 1 bay horse), 1 was a lymphosarcoma, 1 was an adenocarcinoma, and 1 was a basal cell tumor. Forty-five (76%) animals underwent conventional or laser debulking of the tumor prior to bead implantation. Forty of 48 (83%) animals for which long-term follow-up information was available were relapse free 2 years after treatment. This included 20 of 22 animals with spindle cell tumors (including 11/13 horses with sarcoids), 6 of 10 animals with squamous cell carcinomas, 13 of 14 animals with melanomas, and 2 of 3 animals with other tumor types. Adverse effects were minimal.
Conclusions and Clinical Relevance—Results suggest that implantation of cisplatin-containing biodegradable beads, with or without tumor debulking, may be an effective treatment for equidae with various cutaneous neoplasms.
Objective—To determine whether excision was an
acceptable treatment for dermal melanomatosis in
Animals—11 horses with dermal melanomatosis
involving the perineal, perianal, or perirectal region or
ventral surface of the tail in which treatment consisted
of tumor excision.
Procedure—Medical records were reviewed. Followup
information was obtained from owners through
Results—9 of the 11 horses were alive at the time of
follow-up interviews. None of the horses had
regrowth at the surgery site where the primary tumor
was removed. There were no confirmed clinical signs
of internal metastasis.
Conclusions and Clinical Relevance—Results suggest
that excision of dermal melanomatosis in horses
may be a reasonable treatment option. (J Am Vet Med
Objective—To evaluate the use of arthroscopy as the
primary method for removal of large patellar fracture
Animals—5 performance horses of various breeds
with patellar fractures.
Procedure—Clinical signs of lameness, external evidence
of injury, and radiography were used to diagnose
and determine fracture orientation. Arthroscopy
of the stifle joint was performed on the affected limb
with the horse positioned in dorsal recumbency and
under general anesthesia. Progress after surgery was
determined by evaluating medical records and via
telephone conversations with owners.
Results—4 of 5 horses had fractures of the medial
aspect of the patella and 1 horse had a fracture of the
lateral aspect of the patella. There were no postoperative
complications with the joint or the arthroscopic
portal incisions. Recovery periods ranged from 3 to 5
months. All horses recovered completely from
surgery, and performed at the same or higher level of
competition as before arthroscopy.
Conclusions and Clinical Relevance—Femoropatellar
joint arthroscopy is a favorable means by
which evaluation of the stifle joint and removal of
large fracture fragments can be achieved with negligible
postoperative complications. (J Am Vet Med
Objective—To determine whether povidone iodine
ointment or 2 forms of silver sulfadiazine applied topically
to wounds of the distal aspect of the limbs in
horses affect the rate of second intention healing and
to evaluate the additional influence of bandaging with
these antimicrobials on granulation tissue formation.
Animals—6 healthy adult horses.
Procedure—Six standardized 2.5-cm2 skin
wounds/horse were distributed between the dorsomedial
surfaces of the metacarpi and metatarsi. One
of the following 6 treatments was applied to each
wound: 1% silver sulfadiazine cream with bandage,
1% silver sulfadiazine slow-release matrix with bandage,
1% silver sulfadiazine slow-release matrix
without bandage, povidone-iodine ointment with
bandage, untreated control with bandage, and
untreated control without bandage. Wound area,
granulation tissue area, and perimeter were measured
by use of planimetry software applied to digital
images. Exuberant granulation tissue was
excised when present. Days until healing, rate of
healing parameter, rate of contraction, and epithelialization
were compared among wound treatment
Results—Healing parameters and mean days to healing
did not differ significantly among any of the
wound treatment groups. Percentage wound contraction
and rate of epithelialization were similar among
wound treatments. All bandaged wounds produced
exuberant granulation tissue, which was surgically
excised; none of the unbandaged wounds produced
exuberant granulation tissue.
Conclusion and Clinical Relevance—When exuberant
granulation tissue is removed, rates of
epithelialization and wound contraction were not different
among wound treatment groups, whether
bandaged or unbandaged. Topical application of 1%
silver sulfadiazine slow-release matrix on unbandaged
wounds induced the same result as medications
applied beneath bandages, but without exuberant
granulation tissue formation. (Am J Vet Res
Objective—To determine long-term effects of transendoscopic, laser-assisted ventriculocordectomy (LAVC) on airway noise and performance in horses with naturally occurring left laryngeal hemiplegia.
Design—Retrospective case series.
Animals—22 horses with left laryngeal hemiplegia treated by means of LAVC.
Procedures—Medical records were reviewed and initial complaint, intended use of the horse, duration of abnormal airway noise, preoperative performance level, endoscopic findings, surgical procedure, postoperative treatment, and complications were recorded. Follow-up telephone interviews with owners and trainers were conducted to determine time for return to intended use, level of postoperative performance, and percentage reduction in airway noise.
Results—All horses were examined because of excessive airway noise; 10 (45%) had concurrent exercise intolerance. Left ventriculocordectomy was performed in all 22 horses; bilateral ventriculocordectomy (right ventriculocordectomy was done 1 year later) was performed in 1 horse (5%). Complications occurred in 3 (14%) horses. Twenty (91%) horses returned to their intended use. Excessive airway noise was eliminated after surgery in 18 (82%) horses; exercise intolerance improved postoperatively in 8 of 10 horses. Three racing Thoroughbreds returned to racing; 1 additional racehorse returned to racing but required a laryngoplasty 1 year later to continue racing.
Conclusions and Clinical Relevance—Results suggested that LAVC was an effective procedure for elimination of excessive airway noise and improvement of performance in horses with left laryngeal hemiplegia.