To describe clinical findings, treatments, and outcomes for cattle with complete traumatic exungulation.
Record databases of 2 teaching hospitals were searched to identify cattle treated for traumatic exungulation between January 1993 and December 2018. Information about signalment, clinical signs and findings, treatment, and outcome was extracted from the records or obtained by telephone communication with the owner.
Records for 5 bulls, 4 heifers, and 1 cow with a median age of 2 years (range, 1 day to 10 years) and weight of 379.1 kg (range, 30 to 909.1 kg) were reviewed. Duration of clinical signs ranged from ≤ 24 hours to 3.5 days. Five of 7 animals had a lameness score > 3/5. Complete exungulation occurred in 6 medial digits (3 hind limbs and 3 forelimbs) and 5 lateral digits (1 hind limb and 4 forelimbs); 1 calf had complete exungulation of both digits of a forelimb. Treatments included bandaging (n = 9), antimicrobials (9), anti-inflammatories (8), hoof block application to the adjacent digit (7), regional anesthesia (6), cast application (4), curettage of the third phalanx (3), regional antimicrobial perfusion (1), and local application of antimicrobial-impregnated beads (1). All 7 cattle with long-term (≥ 9 months) information available returned to their intended function; 6 had no residual lameness, and 3 required regular corrective trimming of the affected digit.
CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested the prognosis for long-term survival and return to intended function is fair to good for cattle with complete exungulation.
To evaluate potential prognostic indicators for does with pregnancy toxemia (PT) and their offspring.
Retrospective cohort study.
Medical records were searched to identify does with PT. Signalment, history, clinical signs, examination findings, treatments, number of offspring present, and duration of hospitalization for does as well as outcome (death vs survival to hospital discharge) for does and their kids were recorded. Variables of interest were examined for association with outcome by contingency table analyses.
Boer goats were overrepresented, compared with the general population of goats for the facility in the last year of the study. Most (15/36) does had appropriate body condition scores. All pregnancies involved twins (11/56), triplets (37), or quadruplets (7). Neutrophilia (26/26) and hyperglycemia (32/40) were common in does. Most (39/56) does survived to hospital discharge. Does with high BUN concentration and those with serum bicarbonate concentration < 15 mEq/L were more likely to die than does without these findings. Forty-nine does survived to delivery of offspring; survival to discharge for these does was positively associated with outcome of their offspring. Among offspring of dams that survived to their delivery, twins had a higher survival rate than quadruplets. Death was more likely for offspring delivered by cesarean section than for those delivered vaginally.
CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested Boers were more likely to develop PT than goats of other breeds in the population examined at the study hospital. In contrast with other studies, hyperglycemia was common in affected does. Further research is needed to confirm associations with outcome identified in this study.
This article provides information to assist practitioners in the diagnosis, medical, and surgical management of obstructive urolithiasis in miniature pigs. The article focuses primarily on pigs managed as pets because production swine rarely undergo intensive treatment for urolithiasis. As much as possible, the information in this article is based on published literature, but given the limited number of publications addressing obstructive urolithiasis in pigs, some information is based on the authors’ clinical experience. Medical and surgical management of obstructive urolithiasis of pigs is often similar to management in ruminant and small animal species, but differences in swine anatomy, handling, and temperament create unique challenges. Pigs tend to be more difficult to restrain and examine than other livestock and often require heavy sedation or anesthesia to facilitate physical examination and basic diagnostic procedures. Because pigs are monogastrics, some oral treatments used in small animals may be used effectively in pigs. Clinicians should follow AMDUCA and consult the Food Animal Residue Avoidance Databank prior to extralabel drug use because pet pigs are still considered a major food-producing species in the United States.
PROCEDURES Three 5F angiographic catheters of the same length (100 cm) and diameter (0.17 cm) but differing in curvature at the tip were labeled A (straight tip), B (tip bent in 1 place), and C (tip bent in 2 places). During a single anesthetic episode, attempts were made to blindly pass each catheter into the urinary bladder of each goat. Order of catheters used was randomized, and the veterinarian passing the catheter was blinded as to catheter identity. The total number of attempts at catheter passage and the total number of successful attempts were recorded.
RESULTS Catheter A was unsuccessfully passed in all 12 goats, catheter B was successfully passed in 8 goats, and catheter C was successfully passed in 4 goats. The success rate for catheter B was significantly greater than that for catheter A; however, no significant difference was identified between catheters B and C or catheters A and C.
CONCLUSIONS AND CLINICAL RELEVANCE 2 angiographic catheters were identified that could be successfully, blindly advanced in a retrograde direction into the urinary bladder of healthy sexually intact male goats. Such catheters may be useful for determining urethral patency, emptying the urinary bladder, and instilling chemolysing agents in goats with clinical obstructive urolithiasis.
OBJECTIVE To describe concentration-over-time data for ampicillin and sulbactam in the digital and systemic circulations and synovial fluid (SYN) of cattle following a single injection of ampicillin-sulbactam as a regional IV perfusion (RIVP).
PROCEDURES The right hind limb of each cow was aseptically prepared. A tourniquet was applied around the midmetatarsal region, and 1.0 g of ampicillin with 0.5 g of sulbactam in a combined formulation was administered as an RIVP into the dorsal common digital vein (DCDV). Blood samples from the DCDV and jugular vein and SYN samples from the metatarsophalangeal joint of the prepared limb were collected immediately before and at predetermined times for 24 hours after RIVP. One blood sample was obtained from the abaxial proper plantar vein of the lateral digit of the prepared limb 0.25 hours after RIVP. Serum and SYN ampicillin and sulbactam concentrations were determined by high-performance liquid chromatography.
RESULTS Mean ± SD maximum concentration of ampicillin in SYN and serum obtained from the abaxial proper plantar and jugular veins was 1,995 ± 1,011 μg/mL, 5,422 ± 1,953 μg/mL, and 2.5 ± 1.6 μg/mL, respectively. Corresponding serum and SYN concentrations of sulbactam were lower but followed the same pattern over time as those for ampicillin. Synovial fluid ampicillin concentration remained above 8 μg/mL for a mean time of 18.9 hours.
CONCLUSIONS AND CLINICAL RELEVANCE Potentially therapeutic concentrations of ampicillin were achieved in regional serum and SYN samples; SYN concentrations remained at potentially therapeutic values for > 12 hours following RIVP of 1.5 g of ampicillin-sulbactam in the hind limb of healthy cows.
Objective—To evaluate whether pedal bacteremia develops following regional IV perfusion (RIVP) of a 2% lidocaine hydrochloride solution in cattle with deep digital sepsis (DDS) and to determine which bacterial pathogens are most commonly isolated from the pedal circulation.
Design—Prospective observational cohort study.
Animals—9 adult cattle with DDS in 10 limbs and 10 healthy adult cattle with no evidence of lameness or digital infection.
Procedures—Blood samples were obtained aseptically from the dorsal common digital vein immediately following tourniquet application and 30 to 60 minutes after aseptic RIVP with a 2% lidocaine solution. Aerobic and anaerobic bacterial cultures were performed on all samples collected. For cattle with DDS, clinical examination with or without debridement of digital lesions was performed after RIVP.
Results—Bacteria were isolated from pedal blood prior to RIVP in 1 cow with DDS and after RIVP and examination with or without debridement in that cow and 4 additional cattle with DDS. Bacteria were not isolated from any blood sample obtained from the healthy cattle. Of the 8 bacterial isolates identified, 5 were gram-positive facultative anaerobes. Cattle with DDS were significantly more likely to develop bacteremia in the pedal circulation than were healthy cattle following RIVP.
Conclusions and Clinical Relevance—Results indicated that bacteremia may be present in the pedal circulation before and following RIVP and examination with or without debridement in cattle with DDS. Thus, systemic or local antimicrobial treatment might be warranted prior to or concurrently with RIVP in cattle with DDS.
To characterize frontal sinusitis unrelated to standard dehorning procedures in adult beef bulls.
18 beef bulls > 2 years of age treated for frontal sinusitis at a veterinary medical teaching hospital between May 1999 and May 2014.
Medical records were reviewed. Information obtained for each bull included signalment, history, findings from physical examination and diagnostic procedures, treatment, and survival to discharge. Long-term follow-up (≥ 1 year) was obtained from owners by telephone.
18 bulls were included, and 17 were bucking bulls. Median age and duration of signs were 4.5 years and 23 days, respectively. The most common owner complaints were nonspecific signs (eg, separation from the herd, hypo- or anorexia, and weight loss; n = 10) and suspected horn or sinus infection (7). Only 8 bulls had nasal discharge, and only 7 of the 17 bulls for which the rectal temperature was recorded were febrile. Results of radiography indicated frontal sinusitis in 12 of 13 bulls, with increased opacity of the affected sinus (n = 11) noted most commonly. Seventeen bulls were discharged from the hospital alive. Long-term follow-up was obtained for 14 bulls, including 13 bucking bulls. All 14 bulls recovered fully, and 9 of the 13 bucking bulls performed well after treatment.
CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested that frontal sinusitis should be considered as a differential diagnosis in beef cattle examined for nonspecific clinical signs and that, with appropriate treatment, the prognosis is good for long-term survival in affected beef cattle.
To assess signalment, clinical findings, and treatments for New World camelids (NWCs) hospitalized for evaluation and treatment of neonatal disorders and investigate associations between these factors and death during and after hospitalization.
267 NWCs ≤ 30 days of age.
Medical records of a veterinary teaching hospital were retrospectively reviewed to identify NWCs admitted for evaluation and treatment of neonatal disorders between 2000 and 2010. Signalment, physical examination data, diagnostic findings, treatments, and outcomes were recorded. Factors were examined for association with death during hospitalization and the overall hazard of death by use of multivariable logistic regression and Cox proportional hazards analysis, respectively.
The sample comprised alpacas (n = 255) and llamas (12). Median age at admission was 3 days, and median hospitalization time was 2 days; 208 of the 267 (77.9%) neonatal NWCs survived to hospital discharge. Factors associated with increased odds of death during hospitalization included prematurity or dysmaturity, hypothermia, sepsis, toxic changes in neutrophils, and undergoing surgery. The odds of death during hospitalization also increased as anion gap increased. After discharge, 151 of 176 (85.8%) animals had follow-up information available (median follow-up time, 2,932 days); 126 (83%) were alive and 25 (17%) had died. Prematurity or dysmaturity, congenital defects, sepsis, oxygen administration, and undergoing surgery as a neonate were associated with an increased hazard of death; the hazard of death also increased as serum chloride concentration at the time of hospitalization increased.
CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested the prognosis for survival during and after hospitalization is good for most NWCs hospitalized because of neonatal disorders.