Objective—To determine whether bronchial brushings from dogs with chronic cough have increased numbers of goblet cells and WBCs, compared with numbers for healthy dogs, or have differing WBC populations, compared with populations in bronchoalveolar lavage (BAL) fluid obtained from dogs with chronic cough.
Animals—9 healthy dogs and 10 dogs with chronic cough.
Procedure—Specimens were collected by use of bronchoscopy. Cellular composition was determined for brushings, and results from dogs with chronic cough were compared with those from healthy dogs. Cellular composition of brushings was compared with composition of BAL obtained from dogs with chronic cough.
Results—Brushings from healthy dogs contained a median of 2.9 × 106 epithelial cells, comprising 100% epithelial cells (96% ciliated, 3% goblet, and 1% other) and no WBCs. Brushings from dogs with chronic cough had 4.5 × 106 epithelial cells, comprising 93% epithelial cells (86% ciliated, 2% goblet, and 12% other). Dogs with chronic cough had significantly greater percentages of WBCs (7%) and neutrophils (6%), compared with values for healthy dogs. Five dogs with chronic cough had no neutrophilic inflammation evident in BAL, but 4 of these had evidence of neutrophilic inflammation in brushings.
Conclusions and Clinical Relevance—Neutrophils, but not goblet cells, were increased in brushings from dogs with chronic cough. Analysis of bronchial brushings provides information about airway inflammation that differs from that found by examination of BAL in some dogs with chronic cough and is a more sensitive indicator of airway inflammation than cytologic examination of BAL in these dogs.
Objective—To assess the long-term clinical outcome
of horses with distal tarsal osteoarthritis (OA) in which
a 3-drill-tract technique was used to induce arthrodesis
of the affected joints, identify any preoperative or
operative factors associated with outcome, and
describe any complications associated with the technique.
Procedure—Medical records were reviewed for information
on signalment, use, history, physical and
lameness examination findings, surgical technique,
and postoperative care. Radiographs were examined,
and severity of OA was graded. Follow-up information
was obtained through telephone interviews with
owners at least 13 months after the procedure.
Results—32 (59%) horses had a successful outcome,
6 (11%) improved but were not sound after
surgery, and 16 (30%) did not improve following
surgery. Outcome was negatively associated with the
previous use of intra-articular injections. Few postoperative
complications were evident.
Conclusions and Clinical Relevance—Results suggest
that distal tarsal OA in horses can be successfully
treated by means of distal tarsal arthrodesis with
a 3-drill-tract technique. Horses with advanced distal
tarsal OA are likely to have poorer outcomes, and the
procedure will likely be of minimal benefit in horses
with concomitant causes of hind limb lameness prior
to surgery and in horses with preexisting proximal
intertarsal joint disease. (J Am Vet Med Assoc 2003;