Objective—To determine response rates and survival
times for cats with lymphoma treated with the University
of Wisconsin-Madison chemotherapy protocol.
Animals—38 cats with lymphoma.
Procedure—Medical records were reviewed, and
information on age, sex, breed, FeLV and FIV infection
status, anatomic form, clinical stage, and survival
time was obtained. Immunophenotyping was
Results—Mean ± SD age of the cats was 10.9 ± 4.4
years. Overall median survival time was 210 days
(interquartile range, 90 to 657 days), and overall duration
of first remission was 156 days (interquartile
range, 87 to 316 days). Age, sex, anatomic form, and
clinical stage were not significantly associated with
duration of first remission or survival time. Eighteen
of the 38 (47%) cats had complete remission, 14
(37%) had partial remission, and 6 (16%) had no
response. Duration of first remission was significantly
longer for cats with complete remission (654 days)
than for cats with partial remission (114 days). Median
survival time for cats with complete remission (654
days) was significantly longer than median survival
time for cats with partial remission (122 days) and for
cats with no response (11 days).
Conclusions and Clinical Relevance—Results suggested
that a high percentage of cats with lymphoma
will respond to treatment with the University of
Wisconsin-Madison chemotherapy protocol. Age,
sex, anatomic form, and clinical stage were not significantly
associated with duration of first response or
survival time, but initial response to treatment was.
(J Am Vet Med Assoc 2005;227:1118–1122)