Search Results

You are looking at 1 - 1 of 1 items for

  • Author or Editor: Jeffrey S. Smith x
  • Refine by Access: All Content x
Clear All Modify Search



To determine scintigraphic, sonographic, and histologic changes associated with renal autotransplantation in cats.


7 adult specific-pathogen-free cats: 5 males, 2 females, 1 to 9 years old.


Renal autotransplantation was performed by moving a kidney (5 left, 2 right) to the left iliac fossa. Before and at multiple times after surgery, for a total of 28 days, cats were evaluated by B-mode and Doppler ultrasonography, scintigraphy, and renal biopsy.


By 24 hours after surgery, a significant decrease (42%) in mean glomerular filtration rate (GFR) and an increase in mean renal size (81% increase in cross-sectional area) were evident in the transplanted kidney, compared with preoperative values. By postsurgery day 28, reduction in GFR was 23%. Significant changes in renal blood flow velocity were identified in both kidneys. Consistent changes in resistive index or pulsatility index for either kidney could not be identified. When all postoperative histologic data were combined, the histologic score, indicating degree and numbers of abnormalities detected, for the transplanted kidney was significantly higher than that for the control kidney.


Significant changes in renal function, size, and histologic abnormalities develop secondary to acute tubular necrosis in cats after uncomplicated renal autotransplantation.

Clinical Relevance

Evaluation of renal size and function may be of benefit for clinical evaluation of feline renal transplant patients, whereas measurement of the resistive index may be of little clinical value. (Am J Vet Res 1999;60:775–779)

Free access
in American Journal of Veterinary Research