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in Journal of the American Veterinary Medical Association

Summary

Tissue sections from 119 cats that died or were euthanatized (1952-1990) because of toxoplasmosis-like illness were reexamined for Toxoplasma gondii by direct microscopy and immunohistochemical staining with anti-T gondii serum. Clinical and pathologic data from 100 of these cats with histologically verified toxoplasmosis were then analyzed. Of these 100 cats, 36 were considered to have generalized toxoplasmosis, 26 predominantly pulmonary lesions, 16 abdominal, 2 hepatic, 1 pancreatic, 1 cardiac, 2 cutaneous, 7 neurologic, and 9 had neonatal toxoplasmosis. In 14 cats, concurrent microbial infections or other maladies were seen. Cats were 2 weeks to 16 years old (median, 2 years; mean, 4 years). Sixty-five cats were males and 34 were females; sex was not recorded for 1 cat. Of 67 cats that had rectal temperatures recorded, 49 (73%) had fever (40.0 to 41.7 C). Dyspnea, polypnea, and signs of abdominal discomfort were frequently observed. Toxoplasmosis had been confirmed antemortem in 8 cats; 4 had a serum antibody titer to T gondii of ≥ 1:1,024; and T gondii had been found in cytologic evaluation of tracheal aspirates from 2 cats and pleural fluid from 1 cat, as well as in a biopsy specimen of a mesenteric lymph node from another. Of the 15 cats with T gondii serum-antibody titers determined by the Sabin-Feldman dye test, 6 had no antibody detected in 1:4 dilution of their serum. Indirect fluorescent antibody titers were found in 10 of 10 cats' sera tested. Forty-one eyes from 27 of the cats were examined microscopically. Twenty-two of the 27 cats (81.5%) had evidence of intraocular inflammation in one or both eyes. Multifocal iridocyclochoroiditis was the most common lesion and was seen in 18 (81.8%) of the cats with ophthalmitis. The ciliary body was the most often severely affected portion of the uvea. Of the 22 cats with ocular toxoplasmosis, T gondii was found in eyes of 10. Toxoplasma gondii was found in the retina of 5 cats, the choroid of 2, the optic nerve of 1, the iris of 3, and the ciliary body of 4. Toxoplasma gondii was identified in 80% of 55 brains, 70.0% of 90 livers, 76.7% of 86 lungs, 64.4% of 45 pancreata, 62.7% of 59 hearts, 45.8% of 72 spleens, 41.5% of 65 intestines, 17.7% of 61 kidneys, and 60.0% of 30 adrenal glands.

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in Journal of the American Veterinary Medical Association

Summary

Toxoplasmosis was diagnosed histologically in 9 kittens and 1 queen from 5 litters. In litter 1, four 3-month-old Siamese kittens and the queen were affected. The queen died of generalized toxoplasmosis, and her kittens died or were euthanatized 20, 22, or 28 days later. In litter 2, two of 3 Abyssinian 4- and 4.5-month-old kittens died of toxoplasmosis. In litter 3, an Abyssinian, delivered by cesarean section, became ill 17 days after delivery, and died 2 days later because of toxoplasmic hepatitis and pneumonia. In litter 4, three kittens, approximately 1 month old, were shedding Toxoplasma gondii-like oocysts, and the organism was identified histologically in tissues of 1 of them. In litter 5, one 3-week-old kitten out of 4 became ill. Toxoplasma gondii-like oocysts were found in feces and T gondii organisms were found in histologic sections of tissues.

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in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association

Summary

Medical records of 9 cats with chylous ascites that underwent exploratory celiotomy were reviewed. In 7 cats, chylous ascites was associated with intra-abdominal neoplasia: 4 cats had an unresectable tumor (hemangiosarcoma, 3 cats; paraganglioma, 1 cat) within the mesenteric root; 2 had malignant lymphoma of the small intestine and mesenteric lymph nodes; and 1 had lymphangiosarcoma of the abdominal wall. In 2 cats, chylous ascites was associated with nonneoplastic diseases: 1 cat had severe biliary cirrhosis and an extrahepatic portosystemic shunt; the other had steatitis caused by vitamin E deficiency. Three cats were euthanatized or died at the time of surgery, and 5 cats were euthanatized within 3 months of surgery. One cat with malignant lymphoma responded well to chemotherapy and lived for 14 months after surgery.

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in Journal of the American Veterinary Medical Association

Summary

Twelve cats with thymoma were treated hy surgical excision of the tumor alone. None of the cats received radiotherapy or chemotherapy. Two cats died or were euthanatized during the immediate postoperative period: 1 because of postsurgical hemorrhage, and the other because of an associated fungal pleuritis. None of the remaining 10 cats developed evidence of local tumor recurrence or metastases. Six of the cats were alive after follow-up periods ranging from 6 to 36 months (mean, 21 months; median, 21 months). Three cats were euthanatized 18 months, 32 months, and 45 months following surgery for unrelated problems, and 1 cat died as a result of trauma sustained 62 months postoperatively. Myasthenia gravis developed postoperatively in 2 of the cats.

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in Journal of the American Veterinary Medical Association