Objective—To determine prevalence of FeLV infection
and serum antibodies against feline immunodeficiency
virus (FIV) in unowned free-roaming cats.
Design—Cross-sectional serologic survey.
Animals—733 unowned free-roaming cats in
Raleigh, NC, and 1,143 unowned free-roaming cats in
Results—In Raleigh, overall prevalence of FeLV infection
was 5.3%, and overall seroprevalence for FIV
was 2.3%. In Gainesville, overall prevalence of FeLV
infection was 3.7%, and overall seroprevalence for
FIV was 4.3%. Overall, FeLV prevalence was 4.3%,
and seroprevalence for FIV was 3.5%. Prevalence of
FeLV infection was not significantly different between
males (4.9%) and females (3.8%), although seroprevalence
for FIV was significantly higher in male
cats (6.3%) than in female cats (1.5%).
Conclusions and Clinical Relevance—Prevalence of
FeLV infection and seroprevalence for FIV in unowned
free-roaming cats in Raleigh and Gainesville are similar
to prevalence rates reported for owned cats in the
United States. Male cats are at increased risk for
exposure to FIV, compared with female cats. (J Am
Vet Med Assoc 2002;220:620–622)