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  • Author or Editor: G. W. Brumbaugh x
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Summary

Effects of the following treatments on abomasal and duodenal myoelectric activity in yearling cattle were studied: 2 ml of 0.9% sodium chloride solution (nacl); 0.07 mg of bethanechol (bet)/kg of body weight; 0.1 mg of metoclopramide (met)/kg; and 0.07 mg of bethanechol and 0.1 mg of metoclopramide (betmet)/kg. All treatments were administered SC during the early part of phase I of the migrating myoelectric complex. Myoelectric signals were recorded for 4 hours after administration of the treatments from 1 electrode in the antrum and 3 electrodes in the duodenum.

For the antral spike rate (asr), there was no significant difference among treatments during the first hour, but the asr was significantly (P < 0.05) greater during hours 2 to 4 after treatment with betmet, compared with asr. for met alone. The duodenal spike rate (dsr) was significantly (P < 0.05) greater during the first hour after administration of betmet than after the other treatments. After administration of BET, DSR was significantly (P < 0.05) greater than after met or nacl. There was no difference in dsr after met, compared with dsr after nacl. There was no significant difference in dsr among treatments during the second and third hours. The total antegrade propagating spike (tatp) count was greater after administration of betmet in all hours, compared with the other treatments. The ratio of taps to total spikes on the orad-most duodenal electrode was significantly (P < 0.05) greater after betmet during hours 1 and 2.

Free access
in American Journal of Veterinary Research

Summary

To evaluate the effect of ketoprofen on fecal output during secretory diarrhea, 16 calves were given approximately 200 μg of heat-stable Escherichia coli enterotoxin by suckling on 2 occasions. On one day, treatment was not administered. On the other day, either 3 mg of ketoprofen/kg of body weight (n = 8) or 6 mg of ketoprofen/kg (n = 8) was administered 1 hour before and 3 hours after administration of enterotoxin. Fecal output was no different after 8 or 24 hours from calves given 3 mg/kg, but fecal output was less at 8 hours and 24 hours for calves given 6 mg/kg (P = 0.0588), compared with the control day.

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in American Journal of Veterinary Research