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To determine the prognostic value of lactate concentration measurements at admission in cattle with long-bone fractures.


43 cattle with long-bone fractures between July 2016 and Dec 2018.


In this prospective cohort study, lactate concentration was measured in systemic venous blood and locally in capillary blood sampled from the fractured and contralateral limbs of cattle and assessed for outcome prediction. The cutoff value was determined by maximizing the Youden index from receiver-operating characteristic curves. Multivariable logistic regression was employed to verify whether higher lactate concentrations compared with the cutoff value were an independent risk factor for poor outcomes at 30 days or 3 years after admission.


Poor outcome was associated with higher capillary lactate concentration in the fractured limb (P < .001) and greater difference with systemic blood (P = .005). A cutoff value of lactate difference ≥ 2.4 mmol/L (sensitivity = 0.80; specificity = 0.965) between capillary lactate in the fractured limb and systemic blood was the best predictor of death ≤ 30 days after admission (P < .001). Multivariable analysis revealed that this cutoff value was an independent risk factor for 30-day and 3-year outcomes (P < .001).


Admission blood lactate concentration difference ≥ 2.4 mmol/L between the fractured limb and systemic blood was a robust and independent predictor of outcome for cattle of the present report. Lactate metabolism is locally impaired in fractured limbs of nonsurviving or at higher complication risk cattle, which may help identify patients at high risk for poor outcomes.

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in Journal of the American Veterinary Medical Association



3 neonatal female calves (ages, < 1 to 4 days) were examined because of mandibular trauma.


Physical examination indicated that each calf had an open fracture of the mandibular pars incisiva (rostral mandibular fracture) with ventral displacement of the incisors at the affected region. Oral radiographs were obtained for 1 calf and revealed that 5 incisors were fractured at the level of the apical dental buds.


Each calf was anesthetized. The fracture site and surrounding tissues were surgically debrided and flushed with sterile 0.05% chlorhexidine solution. The laceration in the oral mucosa was closed with absorbable suture in an interrupted horizontal mattress pattern. Additionally, a Penrose drain was placed during primary closure and removed 4 days later in 1 calf. The fractured incisors were removed during primary debridement in another calf. All calves received perioperative antimicrobials and analgesics. One calf developed mild osteomyelitis of the rostral mandible, which resolved with additional surgical debridement and antimicrobial treatment. That calf and another developed mild brachygnathia. At the time of last follow-up (3 to 13 months after hospital discharge), all 3 calves were eating and growing as expected.


3 calves with open rostral mandibular fractures were successfully managed by surgical debridement and primary closure of the oral laceration. The procedure was easy to perform, did not require specialized equipment, and was less expensive than other repair methods. This procedure may be an effective and economic on-farm treatment alternative for calves with rostral mandibular fractures.

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in Journal of the American Veterinary Medical Association