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  • Author or Editor: Ellis G. Farstvedt x
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Objective—To compare intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy.

Design—Randomized controlled trial.

Animals—15 mares between 4 and 20 years old.

Procedure—Standard bilateral laparoscopic ovariectomy was performed. Prior to manipulation of the ovary, 2% lidocaine (10 mL) was injected into the ovary and saline (0.9% NaCl) solution (10 mL) was injected into the mesovarium on 1 side, with saline solution (10 mL) injected into the ovary and 2% lidocaine (10 mL) injected into the mesovarium on the other side. Presence (yes vs no) and severity (visual analogue scale) of pain were scored at 5 times (grasping of the ovary, dissection of the mesosalpinx, tightening of the first loop ligature, tightening of the second loop ligature, and transection of the ovarian pedicle) by 2 individuals blinded to treatment and each other's observations.

Results—During 4 of the 5 observation periods, significantly fewer mares had signs of pain following mesovarian injection of lidocaine, and during 2 of the 5 observation periods, visual analogue scale score was significantly lower.

Conclusions and Clinical Relevance—Results suggest that mesovarian injection of lidocaine is associated with significantly lower pain responses, compared with intraovarian injection, in horses undergoing laparoscopic ovariectomy. (J Am Vet Med Assoc 2005;227:593–596)

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in Journal of the American Veterinary Medical Association