Objective—To identify factors associated with leakage
following intestinal anastomosis in dogs and cats.
Animals—90 dogs and 25 cats.
Procedure—Medical records of all dogs and cats that
underwent intestinal resection and anastomosis
between 1991 and 2000 were reviewed, and information
on 27 factors was recorded.
Results—Anastomotic leakage was identified in 13 of
the 90 dogs but in none of the 25 cats. Preoperative
factors significantly associated with development of
anastomotic leakage in dogs included preoperative
peritonitis, serum albumin concentration, a left shift,
and indication for surgery (dogs with intestinal foreign
bodies were more likely to have leakage than dogs
that underwent surgery for any other cause).
Postoperative and case management factors significantly
associated with development of leakage included
duration of hospitalization, supplemental alimentation,
whether the dog ate the day after surgery, blood
product administration, and outcome (died vs survived).
Discriminant analysis was performed, and
dogs with 2 or more of the following factors were predicted
to develop anastomotic leakage: preoperative
peritonitis, intestinal foreign body, and serum albumin
concentration ≤ 2.5 g/dL. The model accurately predicted
whether leakage would develop in 67 of 80
Conclusions and Clinical Relevance—Results suggest
that a variety of factors may be associated with
development of intestinal anastomotic leakage in
dogs. In particular, dogs with 2 or more of the following
risk factors are predicted to be at high risk for
developing anastomotic leakage: preoperative peritonitis,
intestinal foreign body, and serum albumin
concentration ≤ 2.5 g/dL. (J Am Vet Med Assoc 2003;