Search Results

You are looking at 1 - 2 of 2 items for

  • Author or Editor: Don A. Samuelson x
  • Refine by Access: All Content x
Clear All Modify Search

Summary

The anterior chambers in 16 dogs with normotensive eyes and 3 Beagles with glaucomatous eyes were treated with 0, 25, 50, or 100 IU of bovine testicular hyaluronidase. Aqueous outflow resistance was then determined by constant-pressure perfusion of 0.9% NaCl solution for 30 or 60 minutes. In normotensive eyes, 25, 50, or 100 IU of hyaluronidase significantly (P < 0.02) increased the rate of constant-pressure perfusion compared with that of untreated eyes during 30- or 60-minute perfusions. Treatment of glaucomatous eyes with 25, 50, or 100 IU of hyaluronidase did not significantly increase the rate of constant-pressure perfusion over controls during a 30-minute perfusion.

Bovine testicular hyaluronidase at all doses removed the staining of colloidal iron from the trabecular meshwork in normotensive eyes. In Beagles with glaucoma, the trabecular meshworks remained stained with colloidal iron when treated with the hyaluronidase, which suggested that some glycosaminoglycans were resistant to this enzyme's action.

Free access
in American Journal of Veterinary Research

Objective

To determine whether photoreceptor outer segments can be found in aqueous humor from dogs with rhegmatogenous retinal detachment (RRD).

Design

Case series.

Animals

4 dogs with unilateral RRD, 2 dogs with bilateral RRD, 1 dog with unilateral non-RRD, and 1 dog with glaucoma without retinal detachment.

Procedure

Aqueous humor samples were fixed in 2% glutaraldehyde and examined by means of transmission electron microscopy.

Results

Outer segments were found in aqueous humor from 7 of 8 eyes with RRD but were not found in aqueous humor from dogs with non-RRD or glaucoma.

Clinical Implications

Photoreceptor outer segments may move into the anterior chamber of eyes with RRD. (J Am Vet Med Assoc 1997;211:1254–1256)

Free access
in Journal of the American Veterinary Medical Association