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  • Author or Editor: Dayna Goldsmith x
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In the fall of 2016, a 19-month-old 25-kg (55-lb) spayed female crossbred German Shepherd Dog was evaluated because of sudden onset of lethargy and inappetence. In March of the same year, the dog had undergone endoscopic biopsy, and examination of the specimen resulted in a diagnosis of eosinophilic inflammatory bowel disease (IBD). At the time of the evaluation, IBD was being managed medically. This dog had regular access to the outdoors and was known to consume coyote feces. Regular deworming was performed including administration of a 14-day course of fenbendazole (50 mg/kg [22.7 mg/lb], PO, q 24 h) in

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in Journal of the American Veterinary Medical Association


OBJECTIVE To describe the prevalence, histologic characteristics, concomitant abnormalities, and outcomes for various types of mammary gland tumors in companion rats (Rattus norvegicus).

DESIGN Retrospective case series.

ANIMALS 100 client-owned rats.

PROCEDURES Medical records of companion rats that had an SC mass and were examined at a veterinary teaching hospital between 1990 and 2015 were reviewed. Information regarding the signalment, age at mass detection, reproductive sterilization status, histologic diagnosis of the SC mass, location of the initial and all subsequent SC masses, treatments administered, and clinical outcomes was extracted from each record and summarized.

RESULTS 105 SC masses were initially detected in 100 rats. The most prevalent SC mass identified was mammary gland fibroadenoma (56/105 [53%]), followed by mammary gland carcinoma (13/105 [12%]). Overall, 26 of 105 (25%) masses were malignant. Sexually intact males were more likely to have nonmammary SC tumors than sexually intact females. In rats receiving no adjunctive treatment after excision of a mammary gland fibroadenoma (n = 16), a second fibroadenoma was detected 1 to 8 months after initial excision, at a median of 4.5 months after surgery. A concomitant pituitary gland tumor was identified in most rats with mammary gland fibroadenoma (21/28 [75%]) and other types of mammary gland tumors (10/17 [59%]). Fourteen of 35 (40%) rats with mammary gland fibroadenoma had concomitant reproductive tract abnormalities.

CONCLUSION AND CLINICAL RELEVANCE Results suggested that, like other species, companion rats with SC masses should undergo a thorough diagnostic workup that includes histologic examination of the excised mass.

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in Journal of the American Veterinary Medical Association