Objective—To compare surgical site infection and inflammation rates between the use of nonimpregnated (polydioxanone and poliglecaprone 25) versus triclosan-impregnated (polydioxanone and poliglecaprone 25) suture for incisional closure in dogs undergoing a standardized orthopedic procedure (tibial plateau leveling osteotomy [TPLO]).
Design—Retrospective cohort study.
Animals—283 dogs that underwent TPLO between November 2005 and December 2009.
Procedures—Medical records were reviewed for age; body weight; body condition score; use of propofol; perioperative and postoperative administration of antimicrobials; presence of a preoperative infection; use of a jig; technique of joint exploration; type of suture material (triclosan impregnated vs nonimpregnated) used to close the pes anserinus, subcutaneous layer, and subcuticular layer; use of staples or suture to close the skin; and surgery and anesthesia durations. The outcome variables were surgical site inflammation and infection.
Results—Rates of infection and inflammation did not differ between surgeries for which triclosan-impregnated suture was used (n = 159 [8.8%, and 18.8%, respectively]) and those for which nonimpregnated suture was used (112 [10.7% and 15.2%, respectively]). The use of staples, compared with suture, to close the skin significantly decreased the inflammation rate.
Conclusions and Clinical Relevance—Compared with in vitro conditions, in vivo conditions (where the environment is not controlled and triclosan may elute more quickly from the suture) may decrease the antibacterial effectiveness of triclosan-impregnated suture. On the basis of our findings, triclosan-impregnated sutures did not seem to provide an additional benefit for clinical use and cannot be strongly recommended for elective orthopedic procedures in veterinary medicine.
Objective—To determine clinical signs, laboratory
findings, relationship to vaccination, and response to
treatment for type I immune-mediated polyarthritis
(IMPA) in dogs.
Procedure—Clinical records and radiographic reports
from 3 university referral hospitals were reviewed.
Clinical signs, laboratory and investigative findings,
relationship to vaccination, and response to treatment
Results—Clinical signs and initial laboratory and clinical
investigative findings were frequently abnormal
but were nonspecific and not associated with likelihood
of recovery. Time of vaccination was not associated
with onset of disease. Chemotherapeutic
immunosuppression resulted in complete cure in
56% of dogs. Continuous medication was required in
18% (7/39) of dogs, relapses were treated successfully
in 13% (5/39) of dogs, and 15% (6/39) of dogs
died or were euthanatized as a result of disease.
Conclusions and Clinical Relevance—The possible
involvement of vaccination in type I IMPA was not made
clear from this study because of the small population
size. Signalment, clinical signs, and results of diagnostic
tests other than multiple synovial fluid analyses were
generally nonspecific. Most dogs with type I IMPA
responded to initial immunosuppressive treatment, but
31% (12/39) of dogs relapsed, required further treatment,
or both. (J Am Vet Med Assoc 2004;224:1323–1327)
Objective—To evaluate the use of a force plate as a
method for objective gait analysis in adult poultry, to
characterize ground reaction forces (GRFs) produced
in adult chickens during normal walking, and to assess
the variability of GRFs.
Animals—18 clinically normal 5-month-old Brown
Procedure—Vertical, craniocaudal, and mediolateral
GRFs were measured as hens walked across a standard
force plate embedded in the middle of a runway.
Results—All GRFs were significantly affected by
speed, and variability was high. With increasing
speed, overall stance time decreased, but the percentage
of stance time spent in braking or propulsion
remained approximately equal. There was an overall
increase in maximum propulsion force, which was
produced at a greater rate over a shorter time; thus,
propulsion integral decreased. Maximum braking
forces and braking integrals were variable, but the
rate at which the forces were generated increased.
Mediolateral forces were 2 to 3 times greater in hens
than values that have been reported for other species.
Conclusion and Clinical Relevance—A standard
force plate can be used to objectively measure GRFs
in walking adult hens; however, the large variation in
the data suggests that the technique in its current
form would be of limited clinical use. Overall, vertical
and craniocaudal forces had similar characteristics to
those of other species, whereas mediolateral forces
were found to be much greater in chickens than for
other species. (Am J Vet Res 2003;64:76–82)
To determine the outcome in dogs diagnosed with congenital extrahepatic portosystemic shunts (EHPSS) at ≥ 5 years of age treated with medical management only (M) or with surgical attenuation (S). The hypothesis was that dogs undergoing surgical attenuation would have a longer survival time than dogs undergoing medical management only.
351 dogs definitively diagnosed with EHPSS at ≥ 5 years of age.
Medical records from 2009 to 2019 at 16 veterinary teaching hospitals were evaluated. Data collected included signalment, clinical signs at diagnosis, clinicopathologic data, surgical and medical treatments, shunt morphology, clinical signs and medical treatments at 6 to 12 months after diagnosis, and survival time.
351 dogs (M, 119 [33.9%]; S, 232 [66.1%]) were included in the study. Survival time was longer with surgery than medical management (hazard ratio, 4.2; M, 3.4 years; S, 10.9 years). Continued clinical signs at 6 to 12 months after diagnosis were more common with medical management (M, 40% [33/88]; S, 14% [21/155]). Continued medical treatments at 6 to 12 months after diagnosis were more common in the medical management group (M, 78% [69/88]; S, 34% [53/155]). Perioperative mortality rate was 7.3%.
Dogs diagnosed at ≥ 5 years of age with EHPSS have significantly better survival times and fewer clinical signs with surgical attenuation, compared with medical management. Older dogs have similar surgical mortality rates to dogs of all ages after surgical EHPSS attenuation.