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  • Author or Editor: Ann-Marie J. Löfgren x
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To evaluate use of propofol-isoflurane as an anesthetic regimen for cesarean section in dogs and to compare this protocol with epidural analgesia and anesthesia induced with thiopental sodium.


Prospective study.


141 bitches admitted for cesarean section.


General anesthesia was induced with propofol in 141 dogs undergoing cesarean section. After intubation, anesthesia was maintained by means of inhalation of isoflurane (0.5 to 2.0%), administered in a 65:35 mixture of oxygen:nitrous oxide. After induction, 20 minutes were allowed to elapse before delivery of puppies was begun. Viability of neonates was ascertained immediately after surgery. Owners were interviewed by telephone to determine survival of puppies during the postoperative period. Survival rates from this study were compared with those from cesarean section performed on dogs under epidural analgesia or under general anesthesia induced with thiopental sodium.


Induction, maintenance, and recovery were problem free in all bitches. Of 412 puppies delivered by cesarean section, 293 (71%) survived, 13 (3%) were born alive but died within 20 minutes of delivery, and 106 (26%) were stillborn. Survival rate for puppies from dams induced with propofol-isoflurane was similar to that for puppies from dams receiving epidural analgesia. Survival rate for puppies delivered by cesarean section performed on dams under general anesthesia was higher for dams induced with propofol than for dams induced with thiopental sodium.

Clinical Implications—

General anesthesia induced with propofol and maintained with isoflurane is acceptable for performing cesarean section in dogs,. (J Am Vet Med Assoc 1997;211:313–317)

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in Journal of the American Veterinary Medical Association