Objectives—To determine effect of α-tocopherol
supplementation on serum vitamin E concentrations
in Greyhounds before and after a race.
Animals—8 adult racing Greyhounds.
Procedure—Dogs were given 2 capsules of α-tocopheryl
acetate (total, 680 units [0.5 g]) with food that
contained ≤ 15 mg of vitamin E/kg each morning for 7
days. Dogs were exercised in a 30 × 30-m grass paddock
for 15 minutes twice a day and raced for 500 m
twice a week. Blood samples were collected before
and 5 minutes after a race, before supplementation
was begun, and after 7 days of supplementation.
Blood and diet samples were analyzed for tocopherols
and α-tocopheryl acetate.
Results—Before supplementation, serum α-tocopherol
concentration after racing (mean ± SD,
6.7 ± 2.4 mg/L ) was significantly lower than before
racing (12.2 ± 3.1 mg/L). After supplementation, α-
tocopherol concentrations were significantly higher
overall, although values obtained before (26.6 ± 5.2
mg/L) and after (29.8 ± 3.6 mg/L) racing were not significantly
Conclusions and Clinical Relevance—Supplementation
with α-tocopheryl acetate increased serum
α-tocopherol concentrations and eliminated the
decrease in α-tocopherol concentration that was
detected after a race, which may decrease oxidation
during exercise and improve performance or recovery.
(Am J Vet Res 2001;62:1118–1120)