Objective—To compare the rate of gastric emptying
of a semisolid meal by use of the carbon 13-labeled
octanoic acid breath test (13C-OBT) and gastric emptying
ultrasonography (GEU) in dogs.
Animals—10 healthy dogs.
Procedure—Food was withheld from dogs for 12 hours
before ingestion of a test meal (bread, egg, and
skimmed milk) containing 13C-octanoic acid. The gastric
antrum was visualized by use of a 6.5-MHz microconvex
transducer, and the area of the ellipse defined by the
craniocaudal and ventrodorsal diameters of the stomach
was measured. Samples of expired air and antral
images were obtained 30 minutes before ingestion of
the test meal and then every 15 minutes for 4 hours and
every 30 minutes for a further 2 hours. The half-dose
recovery time with the 13C-OBT (t½[BT]) and the gastric
half emtying time withGEU (t50%[GEU]) was calculated.
Results—Mean ± SD values for the t½(BT) and
t50%(GEU) were 3.44 ± 0.48 hours and 1.89 ± 0.78
hours, respectively. A significant correlation was
detected between the t½(BT) and t50%(GEU), although
there was a large (1.55 hours) mean difference
between these indices.
Conclusions and Clinical Relevance—Results indicated
that there was a correlation between the rate of
solid-phase gastric emptying assessed by use of GEU
and the 13C-OBT in dogs. Gastric emptying ultrasonography
may be a useful, noninvasive method for
assessment of the rate of solid-phase gastric emptying
in dogs. (Am J Vet Res 2004;65:1557–1562)