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Abstract

OBJECTIVE

The objective of this study was to evaluate the accuracy of a beta prototype version of a new portable blood glucose meter in feline patients.

ANIMALS

60 client-owned cats.

METHODS

In this prospective study, 3-mL blood samples were collected from each cat and analyzed in triplicate using a beta prototype device (AlphaTRAK 3 [AT3]) and by a reference lab standard immediately after collection. Accuracy of the AT3 device was determined in accordance with the International Organization of Standardization (ISO) 15197:2013 criteria, including Bland-Altman plotting and consensus error grid analysis. A Passing-Bablok regression analysis was also performed.

RESULTS

96% of feline measurements fell within the ISO accuracy threshold, and 100% of measurements fell within zones A and B of the consensus error grid, meeting the ISO accuracy requirements. There was no significant bias in the data according to the Bland-Altman analysis. Within the full range of glucose concentrations (20 to 750 mg/dL) the correlation coefficient between the AT3 and the reference lab standard was 0.99. There was no significant constant or proportional bias present in the data.

CLINICAL RELEVANCE

The AT3 device met the ISO requirements and is accurate for measurement of blood glucose concentrations in cats.

Open access
in Journal of the American Veterinary Medical Association