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- Author or Editor: A. Magnus Rorvik x
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Abstract
Objective—To determine clinical, radiographic, and pathologic abnormalities in dogs with multiple epiphyseal dysplasia (MED).
Design—Retrospective case series.
Animals—19 dogs with MED from 10 litters.
Procedures—The diagnosis was made on the basis of radiographs of the shoulder region and vertebral column. Ten dogs underwent necropsy.
Results—There were 11 Hygenhund, 6 Dunker, 1 Golden Retriever, and 1 English Pointer. Most dogs were examined because of lameness that developed at 5 to 8 months of age. The most common radiographic abnormality was a deficiency in ossification of the epiphyses, apophyses, and cuboidal bones of the appendicular skeleton and the epiphyses of the vertebrae; ossification of the metaphyses and the diaphyses typically were normal. Disease severity was consistent among littermates, but varied among dogs from different litters.
Conclusions and Clinical Relevance—Results suggested that MED is a rare condition in dogs characterized by a deficiency in ossification of the epiphyses of the long bones, the epiphyses of the vertebrae, the cuboidal bones, and the apophyses. Radiographic abnormalities were evident in dogs examined as young as 8 weeks of age, and most dogs had developed severe lameness by 5 to 8 months of age. The condition most likely had an autosomal recessive mode of inheritance, although genetic studies of mode of inheritance could not be performed.
Abstract
Objective—To determine clinical and diagnostic imaging findings in young horses with osteochondral fragments involving the dorsomedial aspect of the proximal interphalangeal (PIP) joint.
Design—Retrospective case series.
Animals—6 horses.
Procedures—Medical records were reviewed. Follow-up information was obtained through telephone conversations with owners or trainers or by examining race records.
Results—Horses were between 1 and 4 years old. Three had bilateral osteochondral fragments in the forelimbs (n = 2 horses) or hind limbs (1). Radiographically, all but 1 fragment seemed to originate from the dorsomedial aspect of the distal end of the first phalanx. Fragment size ranged from 6 × 9mm to 11 × 21 mm. Three horses had lameness referable to the region of the affected joint; the other 3 horses did not have clinical signs referable to affected PIP joints. Two horses were euthanized shortly after diagnosis at the owners' request because of concerns that the horses would be unsuited for their intended athletic use. Two of the 3 horses in which fragments were incidental findings were able to race successfully, although 1 received intra-articular corticosteroid treatments; the third was retired because of unrelated orthopedic problems.
Conclusions and Clinical Relevance—Results suggested that osteochondral fragments involving the dorsomedial aspect of the PIP joint may be an incidental finding in young horses. Given the absence of clinical signs in 5 of 9 affected joints and the fact that 3 of 6 horses were affected bilaterally, a developmental origin of the fragments was suspected.
