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Summary

In the study reported here, 121 Salmonella enteritidis isolates from human beings and 467 isolates from nonhuman sources were analyzed for plasmid pattern and susceptibility to a panel of antimicrobial agents commonly used as biologic markers. A significant (P < 0.05) number of isolates from nonhuman sources were resistant to β-lactam antibiotics and tetracycline. Resistance to aminoglycosides, quinolones, and trimethoprim/sulfamethoxazole was uncommon. Of the 588 isolates, 445 (76%) were resistant to 2 or more antimicrobial agents. Sixty of 121 (50%) S enteritidis isolates from human beings were susceptible to all 12 antimicrobial agents, but 425 of 467 (91%) S enteritidis isolates from nonhuman sources expressed resistance to 1 or more of the antimicrobial agents used in the study. Analysis of plasmid profiles revealed that significantly (P < 0.05) more isolates from nonhuman sources had high molecular weight plasmids than did isolates from human beings. Isolates from ceca of chickens were associated with patterns of low molecular weight plasmids. Analysis of results of the study revealed similarities among S enteritidis from human beings and eggs, as determined on the basis of plasmid profiles and antibiotic susceptibility patterns, which may implicate eggs as one of the potential sources for infection of human beings. In addition, periodic monitoring of a substantial number of Salmonella isolates to detect drug resistance may be a prudent practice for use in revising the list of antimicrobial agents commonly used in human beings and other animals.

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in Journal of the American Veterinary Medical Association

History A 3-year-old sexually intact male Pekingese was evaluated for anorexia, vomiting, and lethargy of 3 days' duration and a history of weight loss of unknown duration. On physical examination, the dog was underweight and had a grade 3

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in Journal of the American Veterinary Medical Association

Fatty Acids The dose of omega-3 fatty acids can be expressed in numerous ways. It can be expressed as the number of milligrams of total omega-3 fatty acids per kilogram of body weight, the number of milligrams of EPA and DHA per kilogram of body weight

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in Journal of the American Veterinary Medical Association

uses slightly different methodologies and reagents, but briefly, the test involves the use of various proteases and other enzymes that digest fructosamine into low-molecular weight fragments. Another enzyme, such as amadoriase, catalyzes these fragments

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in Journal of the American Veterinary Medical Association

, individual animal evaluated for weight gain and pen of animals evaluated for feed efficiency). Table 1— Selected components and methods for a systematic, time-efficient approach to evaluation of the scientific literature to improve clinical decision

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in Journal of the American Veterinary Medical Association