Objective—To compare results obtained by use of laparoscopyassisted abomasopexy versus omentopexy via right flank laparotomy for the treatment of dairy cows with left displaced abomasum (LDA).
Animals—120 dairy cows with an LDA.
Procedure—In a prospective clinical trial, cows were randomly allocated to the abomasopexy group (laparoscopy-assisted abomasopexy) or to the control group (omentopexy via right flank). Data were obtained during the first 5 days after surgery and 6 weeks and 6 months after surgery.
Results—59 of 60 cows in the abomasopexy group and all 60 cows in the control group were treated successfully. Median duration was shorter for the laparoscopic procedure (27.5 minutes), compared with that for the control group (38 minutes). Five cows in the abomasopexy group had wound complications and 2 had LDA relapses, compared with 2 wound complications and no relapses in the control group. During the 5 days after surgery, the abomasopexy group had a significantly higher increase in rate of energy intake and milk yield and a more rapid return to reference range for serum glutamic dehydrogenase activity and total bilirubin concentration, compared with results for the control group.
Conclusions and Clinical Relevance—Success rates were almost equal for both methods. Advantages of the laparoscopic abomasopexy procedure include practicality, low risk of complications, and rapid postoperative recovery. Contraindications are cardiopulmonary diseases. Other disadvantages include the cost of the instruments and inability to perform the procedure in cows with abomasal adhesions.
Objective—To compare the content of substance P, vasoactive intestinal polypeptide, and neurofilament 200 in biopsy specimens taken from the abomasal wall of healthy cows of 2 breeds.
Sample Population—Biopsy specimens taken from different sites of the abomasal wall from 20 German Holstein cows and 20 German Fleckvieh cows.
Procedures—Biopsy specimens were examined immunohistochemically, and the content of substance P, vasoactive intestinal polypeptide, and neurofilament 200 was determined by measuring the immunoreactive areas.
Results—Significant differences between the breeds were detected. Substance P-immuno-reactive area in the corpus abomasi was significantly smaller in the German Holsteins (geometric mean ± geometric SD, 679 ± 1.83 μm2) than in the German Fleckvieh cows (1,020 ± 1.65 μm2). Concerning vasoactive intestinal polypeptide, differences between breeds were not significant. Overall nerve density in the antral abomasal wall was significantly greater in German Holsteins than in German Fleckvieh cows (immunoreactive areas for neurofilament 200 in German Holsteins was 4,842 ± 1.29 μm2 and in German Fleckvieh cows was 3,333 ± 1.63 μm2).
Conclusions and Clinical Relevance—The significantly lower content of substance P in the corpus abomasi could explain why German Holstein cows are predisposed to abomasal displacement, compared with German Fleckvieh cows, in which this disease is a rare finding.
Objective—To determine the correlation between
insulin concentrations and myoelectrical activity of
the abomasum in cows with a left displaced abomasum
Animals—14 dairy cows with an LDA at the onset of
Procedure—During surgical correction of an LDA, 3
pairs of electrodes were placed in the smooth muscle
of the gastrointestinal tract (abomasal body, pars
pylorica, and duodenum) of each cow.
Electromyographic recordings were obtained once
per day for 7 days. Samples were collected and tested
to determine concentrations of insulin, glucagon,
cortisol, glucose, β-hydroxybutyrate, and nonesterified
Results—All 14 cattle had high glucose and insulin
concentrations at the time of admission, independent
of ketosis. Concentrations of glucose and
insulin decreased slowly after surgical treatment and
were associated with a progressive increase in abomasoduodenal
myoelectric activity. The 14 cows
were allocated into 2 groups (suspected insulinresistant
cattle, n = 7; suspected non–insulin-resistant
cattle, 7) on the basis of persistent hyperinsulinemia
during the postoperative period. Seven days
after surgery, the abomasoduodenal myoelectric
patterns were still significantly lower for the insulinresistant
cows, compared with patterns for the
Conclusions and Clinical Relevance—Insulin
resistance appears to be common in cows with an
LDA. Analysis of results of this study reveals that
abomasal atony in cows with an LDA depends on
persistence of high serum concentrations of insulin.
Results of this study could provide an explanation
for a pathogenetic factor of LDAs and the frequent
relapses of cattle affected by this condition. (Am J
Vet Res 2004;65:1319–1324)