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–2015 303 90 2016–2019 358 131 2020–2022 206 135 Total 1,030 447 Table 2 Distribution of minimum inhibitory concentrations necessary to inhibit the growth of 50% and 90% (MIC 50 and MIC 90 , respectively) of E

Open access
in American Journal of Veterinary Research

max ranged from 1.56 to 4.3 hours, and the t ½ was between 1 hour and 3 hours. These values attained the minimum inhibitory concentration (MIC) reported for 100% of pathogenic Aspergillus spp. 17 , 18 , 23 Discussion Voriconazole is

Open access
in American Journal of Veterinary Research

tissues, and the presence of in vitro published minimum inhibitory concentration (MIC) data for ET. 2 , 5 , 13 Broth dilution terbinafine susceptibility testing from 3 clinical ET isolates has demonstrated MICs between 15 and 60 ng/mL. 2 However, oral

Open access
in American Journal of Veterinary Research

general tolerability and broad spectrum of activity. 15 Their bacterial killing properties are dependent on the amount of time that the concentration of the antimicrobial is greater than the minimum inhibitory concentration (MIC) of the infecting pathogen

Open access
in American Journal of Veterinary Research

and Fusarium , suggesting prevalent resistance ( Table 1 ) . Consequently, clinicians are more often opting for newer azoles with superior susceptibility, such as voriconazole. 3 , 7 , 10 , 12 Table 1 Minimum inhibitory concentrations (µg

Open access
in Journal of the American Veterinary Medical Association

grade with survival. Antimicrobial susceptibility data for the E coli isolates were presented as minimum inhibitory concentration (MIC) frequencies and percentage of susceptible isolates. Feline plasma MIC breakpoints were used when available. 22

Open access
in Journal of the American Veterinary Medical Association

antimicrobial concentrations will be above the minimum inhibitory concentration (MIC) for susceptible bacteria. Breakpoint dosage regimens can be found in breakpoint documents. 47 , 48 Understanding antimicrobial resistance trends, surveillance data, and

Open access
in Journal of the American Veterinary Medical Association

medical practitioners select antimicrobials judiciously. The use of AST requires the measurement of either minimum inhibitory concentrations (MICs) via dilution series or zones of inhibition via disk diffusion. This measurement is an in vitro evaluation

Open access

drug concentration (C MAX ) to the minimum inhibitory concentration (MIC) results in an improved bactericidal effect. 19 , 20 For susceptible pathogens, the MIC for amikacin is considered to be ≤ 4 µg/mL, while 8 µg/mL is considered intermediate

Open access
in American Journal of Veterinary Research

a higher minimum- inhibitory concentration for the drug compared to the closely related CTX-M-14. 47 Studies investigating the role of certain veterinary drugs in the emergence of particular ESBL enzymes are lacking. Ceftazidime use is prohibited in

Open access
in American Journal of Veterinary Research