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: 9524075 . doi: 10.1155/2018/9524075 13. Deimel LP , Li Z , Ranasinghe C . Interleukin-13 as a target to alleviate severe coronavirus disease 2019 and restore lung homeostasis . J Clin Transl Res . 2021 ; 7 ( 1 ): 116 – 120 . 14. Peng H

Open access
in American Journal of Veterinary Research

interleukin-1β (IL-1β), the central inflammatory cytokine in osteoarthritis, exhibit a marked decrease in aggrecan gene expression; whereas MPA treatment when combined with IL-1β exposure restored the aggrecan gene expression to that of chondrocytes maintained

Open access
in American Journal of Veterinary Research

Interleukin (IL)-8 concentration in cats with neoplasia, comparing those with metastatic disease to those without metastases. The concentration of Interleukin-8 was found to be higher in cats with radiologically suspected metastatic tumors compared with cats

Open access
in American Journal of Veterinary Research

proinflammatory cytokines such as interleukin-1β (IL-1β), tumor necrosis factor-α (TNFα), and interferon-γ (IFNγ), 9 as well as increased parathyroid hormone (PTH) levels. 10 A recent study 11 in a rodent CKD model with nonregenerative anemia showed the

Open access
in American Journal of Veterinary Research
Author:

meniscal injuries and osteoarthritis in horses. 13 Equine MSCs demonstrate immunomodulatory effects through inhibition of lymphocyte proliferation and induction of interleukin (IL)-10. 17 In rabbit ocular models, MSCs have been shown to accelerate corneal

Open access
in American Journal of Veterinary Research

-stimulating factor (GM-CSF) pretreated and lipopolysaccharide + interferon gamma (LPS+IFN-γ)-primed or proinflammatory, and interleukin-4 and interleukin-10 (IL-4+IL-10)-primed or regulatory macrophages, recently characterized by our group, 21 were co-cultured with

Open access
in American Journal of Veterinary Research

study had the following 3 objectives: (i) to determine whether dogs with CYB5R deficiency have a constitutive proinflammatory phenotype by comparing plasma levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10), and serum

Open access
in American Journal of Veterinary Research

articular cartilage. Thus, the objective of this study was to determine whether BoNT-A exerts any effects on equine articular cartilage in vitro. Effects of equine recombinant interleukin 1 (rEq IL-1) on cartilage matrix homeostasis and chondrocyte

Open access
in American Journal of Veterinary Research

oral NSAIDs, corticosteroids, and sodium hyaluronate; and biologics such as platelet-rich plasma, mesenchymal stromal cells, interleukin (IL)-1 receptor antagonist protein, and others. 10 – 17 Most of these treatments decrease pain, but do not

Open access
in American Journal of Veterinary Research
Authors and

necrosis factor-α (TNF-α), and interleukin-17A (IL-17A) have a central role in the pathogenesis of pulmonary fibrosis by stimulating fibroblast proliferation and increasing collagen accumulation. 10 – 12 , 17 Haptoglobin (Hp) is a positive (upregulated

Open access
in American Journal of Veterinary Research