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, increased thirst and urination, jaundice, lethargy, and vomiting. Doberman Pinschers are among dog breeds with predispositions toward copper-associated liver disease, but scientists at Cornell University warn that high copper concentrations in dog diets

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T he recently identified diet-associated dilated cardiomyopathy (DCM) has been linked to an intake of diets high in pulses (ie, peas, lentils, chickpeas, and dry beans) and, to a lesser degree, potatoes and sweet potatoes. 1 – 3 There have been

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in American Journal of Veterinary Research

identified in 21 dogs (14.4%), including 9 dogs (6.2%) with DCM ( Supplementary Video S1 ) and 9 dogs (6.2%) with stage B1 MMVD. The mean age of dogs with DCM was 5.7 ± 2.3 years and 8/9 dogs were male. Seven dogs with DCM were eating a diet that met World

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in American Journal of Veterinary Research

Abstract

Objective—To evaluate plasma taurine concentrations (PTC), whole blood taurine concentrations (WBTC), and echocardiographic findings in dogs fed 1 of 3 protein-restricted diets that varied in fat and L-carnitine content.

Animals—17 healthy Beagles.

Design—Baseline PTC and WBTC were determined, and echocardiography was performed in all dogs consuming a maintenance diet. Dogs were then fed 1 of 3 protein-restricted diets for 48 months: a low-fat (LF) diet, a high-fat and L-carnitine supplemented (HF + C) diet, or a high-fat (HF) diet. All diets contained methionine and cystine concentrations at or above recommended Association of American Feed Control Officials (AAFCO) minimum requirements. Echocardiographic findings, PTC, and WBTC were evaluated every 6 months.

Results—The PTC and WBTC were not significantly different among the 3 groups after 12 months. All groups had significant decreases in WBTC from baseline concentrations, and the HF group also had a significant decrease in PTC. One dog with PT and WBT deficiency developed dilated cardiomyopathy (DCM). Taurine supplementation resulted in significant improvement in cardiac function. Another dog with decreased WBTC developed changes compatible with early DCM.

Conclusion and Clinical Relevance—Results revealed that dogs fed protein-restricted diets can develop decreased taurine concentrations; therefore, protein-restricted diets should be supplemented with taurine. Dietary methionine and cystine concentrations at or above AAFCO recommended minimum requirements did not prevent decreased taurine concentrations. The possibility exists that AAFCO recommended minimum requirements are not adequate for dogs consuming protein-restricted diets. Our results also revealed that, similar to cats, dogs can develop DCM secondary to taurine deficiency, and taurine supplementation can result in substantial improvement in cardiac function. (Am J Vet Res 2001;62:1616–1623)

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in American Journal of Veterinary Research

Response Network analyzed records from 161 dogs. Of 121 dogs with DCM reports sent to the FDA between January 2018 and April 2019, 23 had full recoveries and 84 had partial recoveries. “All dogs that fully recovered received a diet change,” the

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in American Journal of Veterinary Research

dilated cardiomyopathy (DCM) and delay the onset of clinical signs. 24 Pimobendan has also been shown to prolong the preclinical period in dogs with myxomatous mitral valve disease with echocardiographic and radiographic evidence of cardiomegaly by 15

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in American Journal of Veterinary Research

dogs, 12 had myxomatous mitral valve disease, 1 had ventricular tachycardia of unknown cause, 1 had DCM, 1 had primary atrial fibrillation, and 1 had mitral dysplasia. The ISACHC III group included 11 dogs (8 sexually intact males and 3 spayed females

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in American Journal of Veterinary Research

Boxers and Doberman Pinschers are frequently affected with cardiomyopathy, although the forms of the disease in these breeds (DCM or ARVC) may have somewhat different characteristics. 1-3 Ventricular arrhythmias are common in both forms: DCM

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in American Journal of Veterinary Research

I nvestigations into a potential link between consumption of grain-free (GF), high-pulse diets, and the development of a dilated cardiomyopathy (DCM) phenotype in dogs have been ongoing since 2018. 1 – 7 Pulse ingredients are defined as dry

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in American Journal of Veterinary Research

, tubes were centrifuged and serum was separated and stored at −80 °C until metabolomics analysis as a single batch. Nutritional assessment was performed in all dogs, including body weight, body condition score (BCS, 1–9 scale), 15 MCS, 14 and diet

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in American Journal of Veterinary Research