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normally distributed (Shapiro-Wilk test), and results were expressed as mean ± SD. Groups were compared by use of a Student t test for dependent samples (Spanish Greyhounds after exercise vs at rest) and a Student t test for independent samples (Spanish

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in American Journal of Veterinary Research

SUMMARY

Twenty-four horses were randomly allocated to 3 groups. All horses underwent a ventral midline celiotomy, and the large colon was exteriorized and instrumented. Group-1 horses served as sham-operated controls, group-2 horses underwent 6 hours of colonic ischemia, and group-3 horses were subjected to 3 hours of ischemia and 3 hours of reperfusion. Baseline blood samples were collected, then low-flow colonic ischemia was induced in horses of groups 2 and 3 by reducing colonic arterial blood flow to 20% of baseline. All horses were monitored for 6 hours. Citrated systemic venous ( sv ) blood samples were collected from the main pulmonary artery, and colonic venous (cv) samples were collected from the colonic vein draining the ventral colon. Samples were collected at 0, and 2, 3, 3.25, 4, and 6 hours for determination of one-stage prothrombin time, activated partial thromboplastin time, antithrombin III activity, and fibrinogen concentration. Data were analyzed statistically, using two-way anova for repeated measures, and post-hoc comparisons were made by use of Student Newman Keul's test. Statistical significance was set at P < 0.05. There were significant decreases in all hemostatic variables by 2 hours in sv and cv samples from horses of all 3 groups, but there were no differences among the 3 groups for any of these variables. These hemostatic alterations could have been secondary to a hypercoagulable state or to fluid therapy-induced hemodilution. Colonic ischemia-reperfusion was not the cause of these alterations because these alterations also were observed in the sham-operated control horses. Significant temporal alterations existed even after accounting for the hemodilution. The most plausible explanation for these alterations is that hemostatic activation was incited by the celiotomy and manipulation of the colon during exteriorization and instrumentation. Comparison of paired sv and cv samples for each hemostatic variable revealed significant differences for the absolute values of one-stage prothrombin time and fibrinogen concentration, but not for activated partial thromboplastin time or antithrombin III activity. This indicates that monitoring sv hemostatic variables does not necessarily provide an accurate assessment of hemostatic function in regional vascular beds. Largecolon ischemia with or without reperfusion did not alter hemostatic function.

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in American Journal of Veterinary Research

derivation. When a specific effect of time was detected during the analysis, a post hoc Student t test for paired samples was used to assess differences between each time point during the 10-minute examination period and the baseline value. Furthermore, a

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in American Journal of Veterinary Research

of FGF-19 concentration. Materials and Methods Animals Ten healthy staff- and student-owned dogs from the Louisiana State University School of Veterinary Medicine were included in the study. Inclusion in the study required that each dog

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in American Journal of Veterinary Research

approximately 20% of all dogs undergoing assessment would have high plasma U:UH 2 concentration ratios. Materials and Methods Dogs —Client-owned dogs evaluated at the University of Georgia Veterinary Teaching Hospital and dogs used in veterinary student

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in American Journal of Veterinary Research

. Effects of time were specified first by graphic assessment and verified by stepwise model derivation. When a significant effect of time was detected during LMM analysis, a post hoc Student t test for paired samples was used to assess differences between

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in American Journal of Veterinary Research

determination of differences between means, which were determined with a Student modified t test by use of the Bonferroni correction for multiple comparisons between means and the error mean square term from the ANOVA. 17 Values of P < 0.05 were considered

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in American Journal of Veterinary Research

effort for repeated measures on calves and a random effect for each day of the study. Student t tests were used to evaluate differences in nasal submucosal and rectal temperatures for each LWSI category. For all multiple comparisons, values of P < 0

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in American Journal of Veterinary Research

healthy adult cats owned by veterinarians, veterinary technicians, and veterinary students at the Purdue University Veterinary Teaching Hospital were used in the study. Median age of the cats was 8.50 years (range, 5 to 14 years), and all 10 were neutered

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in American Journal of Veterinary Research

differences for each velocity step of the IET, followed by the Tukey test when necessary. A Student t test for paired samples was also performed to compare differences among groups. A value of P ≤ 0.05 was considered significant. Results Evaluation

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in American Journal of Veterinary Research