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) and in BW from 11.6 to 18.1 kg (mean, 15.1 kg). Dogs were obtained from the Department of Clinical Sciences of Companion Animals of Utrecht University. The dogs were used for teaching students in clinical diagnostics and for minor noninvasive studies

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in American Journal of Veterinary Research

degeneration). Four observers (a veterinary medical student, a student in a PhD program, a board-certified veterinary surgeon, and a board-certified veterinary radiologist) separately graded the MRI images: none of the observers were aware of the source of the

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in American Journal of Veterinary Research

cats in the liver and renal cortex were analyzed with the Student t test with 2-tailed P values and 1-sample t test of the difference between 2 injections. Analysis of variance with repeated measurements and Student t test were used to compare

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in American Journal of Veterinary Research

normal and affected dogs by use of the Student t test. Once the more uniform reference organ was identified, it was used to calculate the hepatic portal perfusion values. To determine differences between clinically normal and affected dogs with regard

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in American Journal of Veterinary Research

teaching students in clinical diagnostic exercises and for minor noninvasive studies. During their stay in the department, all dogs received the best standard of care. The experimental protocols of this study were approved by the Ethical Committee of the

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in American Journal of Veterinary Research

-weighted MRI images were graded separately by 3 observers: a veterinary medical student (observer 1), a student in a PhD program (observer 2), and a board-certified veterinary radiologist (observer 3). The MRI images were examined on standard computer

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in American Journal of Veterinary Research

analysis —Statistical analyses were performed with software. i Differences in CrC, RF, and CF volume between healthy control and CC-affected sheep were analyzed via a paired Student t test for continuous variables. Correlations for continuous variables

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in American Journal of Veterinary Research

first set of baseline and postdiuretic BOLD images were evaluated by a fourth-year PhD student (S-KL) and veterinarian with 1 year of radiology experience (JRL) under the supervision of a veterinary radiologist (JHC). Placement of each ROI over the renal

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in American Journal of Veterinary Research

Student t test was used to compare mean SNRs at various time points; mean CNRs were similarly compared. A paired t test was used for repeated measures to determine the earliest time at which a plateau in signal intensity measurements was achieved (ie

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in American Journal of Veterinary Research

through the use of an installed software program h by a veterinarian who was a fourth-year PhD student (SP) and a veterinarian with 2 years of radiology experience (J-WJ). A window width of 400 HU and window level of 100 HU were used for image review

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in American Journal of Veterinary Research