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Rapamycin, also known as sirolimus, was first isolated from Streptomyces hygroscopicus on Easter Island in the mid-1970s 1 and was initially characterized as an antifungal and antimicrobial agent. Since then, its immunosuppressant and

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in American Journal of Veterinary Research

Shinohara ET Moretti L , et al. The role of mTOR inhibition in augmenting radiation induced autophagy . Technol Cancer Res Treat 2007 ; 6 : 433 – 448 . 53. Sarkaria JN Schwingler P Schild SE , et al. Phase I trial of sirolimus combined

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in American Journal of Veterinary Research