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result in osteomyelitis, septic arthritis, and septic tenosynovitis, which are collectively known as deep digital sepsis. These conditions are among the most debilitating causes of lameness, often resulting in substantial loss of function or destruction

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in American Journal of Veterinary Research

Osteomyelitis and infections associated with orthopedic implants are common complications following fracture repair and are often difficult to treat successfully. In 1 study, 1 53 of 192 (28%) horses developed a postoperative infection following

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in American Journal of Veterinary Research

medical problems in companion rabbits is dental disease, and common sequelae to dental disease in rabbits are periapical tooth infections, bacterial osteomyelitis, and facial abscess formation. 3 Such abscesses result in considerable morbidity and death

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in American Journal of Veterinary Research

arthritis, septic tenosynovitis, and septic pedal osteitis or osteomyelitis and are collectively referred to as DDS. 3–5 In cattle, lesions associated with DDS are some of the most severe and painful causes of lameness. 6–8 Treatment goals for DDS include

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in American Journal of Veterinary Research

osteomyelitis, 22 multiple fistulas, 22,29 rhinitis, 30 and cystitis 24,31 and horses with metritis. 32 Buffered chelators reportedly have minimum adverse effects when used in joints, 22 bones, 22 the uterus, 32 ears, 23,25,28 the bladder, 24,31 and

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in American Journal of Veterinary Research

Lavoie JP . Septic arthritis in 15 standardbred racehorses after intra-articular injection . Equine Vet J 1992 ; 24 : 430 – 434 . 10.1111/j.2042-3306.1992.tb02872.x 4. Martens RJ Auer JA . Hematogenous septic arthritis and osteomyelitis in

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in American Journal of Veterinary Research

—state-of-the-art . J Small Anim Pract 1995 ; 36 : 395 – 399 . 10.1111/j.1748-5827.1995.tb02962.x 16. Barth RE , Vogely HC , Hoepelman AIM , et al. ‘To bead or not to bead?’ treatment of osteomyelitis and prosthetic joint-associated infections with

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in American Journal of Veterinary Research

of leakage under the tourniquet . Anesthesiology 1986 ; 65 : 316 – 320 . 10.1097/00000542-198609000-00014 34. Finsterbusch A Weinberg H . Venous perfusion of the limb with antibiotics for osteomyelitis and other chronic infections . J

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in American Journal of Veterinary Research

other local delivery techniques 23,24 and offer advantages in the treatment of patients with septic arthritis complicated by osteomyelitis. One aspect of continuous IA infusion of antimicrobials that requires further investigation is the type of

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in American Journal of Veterinary Research

.1016/S0946-672X(02)80051-7 39. Güzel Y , Golge UH , Goksel F , The efficacy of boric acid used to treat experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus : an in vivo study . Biol Trace Elem Res 2016 ; 173

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in American Journal of Veterinary Research