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. 16 Prophylactic intragastric administration of GaM to experimentally infected mice reduced their R equi tissue burdens. 10 The study reported here was designed to determine the pharmacokinetics of intragastrically administered GaM in neonatal

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in American Journal of Veterinary Research

total dose as regimen 1 but were chosen to allow for comparison with results reported by other authors who used similar doses. The regimens in the study reported here also avoided fluoroquinolone toxicosis in neonates 4 that is possible at a higher dose

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in American Journal of Veterinary Research

parameters differed. Although the terminal half-life of CCFA is similar for all mammals evaluated, 17,18,22–26 the T max was much shorter in the rabbits of the present study, compared with findings for other evaluated species except neonatal foals. This may

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in American Journal of Veterinary Research

.40.1.61 12. Hewson J , Johnson R , Arroyo LG , et al. Comparison of continuous infusion with intermittent bolus administration of cefotaxime on blood and cavity fluid drug concentrations in neonatal foals . J Vet Pharmacol Ther 2013 ; 36

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in American Journal of Veterinary Research

associated with food-animal neonates result from gram-negative organisms and the ensuing host inflammatory response. 32 Therefore, development of novel interventions that can moderate the inflammatory response elicited by LPS remains an important animal

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in American Journal of Veterinary Research

from cattle. It is possible that differences in species specificity might affect the ability of bacterial strains in a DFM to colonize the gastrointestinal tract. In human neonates, E coli are among the first bacteria to colonize the gut 48

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in American Journal of Veterinary Research

interactions) that obstructed the pulmonary microvasculature during autopsy. 3 In another study 5 of human neonates who died after concomitant administration of incompatible drugs, crystalline material or white precipitates were frequently found in vascular

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in American Journal of Veterinary Research

-hemolytic Escherichia coli associated with diarrhea in neonatal swine . J Clin Microbiol 2002 ; 40 : 389 – 394 . 10.1128/JCM.40.2.389-394.2002 4 Harada K , Asai T , Kojima A , et al. Antimicrobial susceptibility

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in American Journal of Veterinary Research

intravenous and intramuscular administration to neonatal calves . Vet J 2005 ; 169 : 437 – 443 . 10.1016/j.tvjl.2004.03.001 43. Brown MP , Mayo MB , Gronwall RR . Serum and synovial fluid concentrations of ampicillin trihydrate in calves with

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in American Journal of Veterinary Research

. Neonatal equine herpesvirus type 1 infection on a Thoroughbred breeding farm . J Vet Intern Med 1998 ; 12 : 36 – 41 . 10.1111/j.1939-1676.1998.tb00494.x 6. Garré B , Shebany K , Gryspeerdt A , et al. Pharmacokinetics of acyclovir after

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in American Journal of Veterinary Research