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in horses 15 ; therefore, skeletal muscle mass is ultimately determined by the balance between the rates of muscle protein synthesis and breakdown. 16 Muscle protein synthesis is regulated through the mTOR-mTORC1 signaling pathway. The upstream

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in American Journal of Veterinary Research

modulated by a series of intracellular signaling cascades that are associated with the mTOR pathway (formerly mammalian target of rapamycin pathway). 10,11 The mTOR pathway regulates translation initiation and has been the subject of recent reviews. 10

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in American Journal of Veterinary Research

intracellular signaling cascades that are associated with the mTOR pathway. The upstream signaling pathways and downstream effectors of the mTOR pathway and the effects of various anabolic stimuli on mTOR-dependent signaling have been the subject of several

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in American Journal of Veterinary Research

breakdown have been reviewed in other reports. 18,19 Protein synthesis is regulated through the mTOR (formally mammalian target of rapamycin) signaling pathway. 19 The factors Akt, 4E-BP1, and rpS6 in horses have been evaluated in another study 20

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in American Journal of Veterinary Research