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and urine interleukin-1b concentrations, which in turn promote hepatic production of fibrinogen, and localized inflammation of the urinary bladder allows fibrinogen to cross the bladder wall and increase uFIB. 6 Subsequent colonization of the urinary

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in American Journal of Veterinary Research

present study would have better represented inflammation in AKI. Interleukin-6 is an important proinflammatory cytokine in the kidneys, and release of IL-6 is stimulated by TNF-α. In several studies, 14,16,31,32 plasma IL-6 concentrations were increased

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in American Journal of Veterinary Research

specific profibrotic and proinflammatory mediators in cats with CKD. For example, compared with clinically normal cats, cats with CKD have higher urine concentrations of TGF-β1 and interleukin-8 and lower urine concentration of VEGF-A, 18 , 19 and these

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in American Journal of Veterinary Research

al . Molecular analysis of adrenergic receptor genes and interleukin-4/interleukin-4 receptor genes in patients with interstitial cystitis . J Urol 2002 ; 168 : 2668 – 2671 . 10.1016/S0022-5347(05)64241-3 11 Ansah OB Raekallio M Vainio

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in American Journal of Veterinary Research